Utilization of Psychotropic Medications and Polypharmacy Among Adults in Jazan Region, Saudi Arabia

Globally, there has been a surge in the prevalence of mental health disorders, not excluding Saudi Arabia. The availability of newer psychotropic medications has led to increased prescribing and polypharmacy. In Saudi Arabia, exploration of the knowledge gap between the outpatient use of psychotropi...

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Autores principales:	Abdulkarim M. Meraya, Monira Alwhaibi, Mamoon H Syed, Ali Shwihi, Muath Mashraqi, Rina Tripathi, Yasser Buayti, Dhaifallah Moraya
Formato:	article
Lenguaje:	EN
Publicado:	Universitas Gadjah Mada 2020
Materias:	behavioral/mental illnesses drug use evaluation electronic health records psychotropic polypharmacy. Pharmacy and materia medica RS1-441
Acceso en línea:	https://doaj.org/article/84079429b6094795a6abe4aaf546d915
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spelling	oai:doaj.org-article:84079429b6094795a6abe4aaf546d9152021-11-15T06:08:47ZUtilization of Psychotropic Medications and Polypharmacy Among Adults in Jazan Region, Saudi Arabia2338-94272338-948610.22146/ijp.813https://doaj.org/article/84079429b6094795a6abe4aaf546d9152020-09-01T00:00:00Zhttps://jurnal.ugm.ac.id/v3/IJP/article/view/813https://doaj.org/toc/2338-9427https://doaj.org/toc/2338-9486Globally, there has been a surge in the prevalence of mental health disorders, not excluding Saudi Arabia. The availability of newer psychotropic medications has led to increased prescribing and polypharmacy. In Saudi Arabia, exploration of the knowledge gap between the outpatient use of psychotropic medications and the extent of polypharmacy has been scarce in the literature. This study evaluated the prescription pattern of psychotropic medications and the prevalence of psychotropic polypharmacy among adult patients with behavioral/mental illnesses. The study was conducted in the psychiatric outpatient clinics of five hospitals in Jazan Region of Saudi Arabia. A retrospective cross-sectional study was conducted with a non-random sample of adults with behavioral/mental illnesses. Psychotropic polypharmacy was the presence of ≥2 psychotropic medication prescriptions. We conducted multivariable logistic regression models to examine the factors associated with psychotropic polypharmacy. A total of 3.052 adults with a behavioral/mental illness were included in the study. Of these, 74.6% had antidepressant prescriptions. The second most prescribed drug class was antipsychotics (51.9%). Furthermore, 65.3% had psychotropic polypharmacy, and 48.2% had interclass psychotropic polypharmacy. Adults with anxiety and other mood disorders were less likely to engage in psychotropic polypharmacy and interclass polypharmacy use than those with depression. However, adults with schizophrenia (adjusted odds ratio [AOR]: 1.91; p<0.001) were more likely to engage in interclass polypharmacy use than those with depression. Adults with behavioral/mental illnesses in Jazan Region of Saudi Arabia have high rates of antidepressants and antipsychotics use. Additionally, psychotropic polypharmacy is a common prescribing practice, and further evaluation of the safety profile of these combinations is warranted.Abdulkarim M. MerayaMonira AlwhaibiMamoon H SyedAli ShwihiMuath MashraqiRina TripathiYasser BuaytiDhaifallah MorayaUniversitas Gadjah Madaarticlebehavioral/mental illnessesdrug use evaluationelectronic health recordspsychotropic polypharmacy.Pharmacy and materia medicaRS1-441ENIndonesian Journal of Pharmacy, Pp 205-216 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	behavioral/mental illnesses drug use evaluation electronic health records psychotropic polypharmacy. Pharmacy and materia medica RS1-441
spellingShingle	behavioral/mental illnesses drug use evaluation electronic health records psychotropic polypharmacy. Pharmacy and materia medica RS1-441 Abdulkarim M. Meraya Monira Alwhaibi Mamoon H Syed Ali Shwihi Muath Mashraqi Rina Tripathi Yasser Buayti Dhaifallah Moraya Utilization of Psychotropic Medications and Polypharmacy Among Adults in Jazan Region, Saudi Arabia
description	Globally, there has been a surge in the prevalence of mental health disorders, not excluding Saudi Arabia. The availability of newer psychotropic medications has led to increased prescribing and polypharmacy. In Saudi Arabia, exploration of the knowledge gap between the outpatient use of psychotropic medications and the extent of polypharmacy has been scarce in the literature. This study evaluated the prescription pattern of psychotropic medications and the prevalence of psychotropic polypharmacy among adult patients with behavioral/mental illnesses. The study was conducted in the psychiatric outpatient clinics of five hospitals in Jazan Region of Saudi Arabia. A retrospective cross-sectional study was conducted with a non-random sample of adults with behavioral/mental illnesses. Psychotropic polypharmacy was the presence of ≥2 psychotropic medication prescriptions. We conducted multivariable logistic regression models to examine the factors associated with psychotropic polypharmacy. A total of 3.052 adults with a behavioral/mental illness were included in the study. Of these, 74.6% had antidepressant prescriptions. The second most prescribed drug class was antipsychotics (51.9%). Furthermore, 65.3% had psychotropic polypharmacy, and 48.2% had interclass psychotropic polypharmacy. Adults with anxiety and other mood disorders were less likely to engage in psychotropic polypharmacy and interclass polypharmacy use than those with depression. However, adults with schizophrenia (adjusted odds ratio [AOR]: 1.91; p<0.001) were more likely to engage in interclass polypharmacy use than those with depression. Adults with behavioral/mental illnesses in Jazan Region of Saudi Arabia have high rates of antidepressants and antipsychotics use. Additionally, psychotropic polypharmacy is a common prescribing practice, and further evaluation of the safety profile of these combinations is warranted.
format	article
author	Abdulkarim M. Meraya Monira Alwhaibi Mamoon H Syed Ali Shwihi Muath Mashraqi Rina Tripathi Yasser Buayti Dhaifallah Moraya
author_facet	Abdulkarim M. Meraya Monira Alwhaibi Mamoon H Syed Ali Shwihi Muath Mashraqi Rina Tripathi Yasser Buayti Dhaifallah Moraya
author_sort	Abdulkarim M. Meraya
title	Utilization of Psychotropic Medications and Polypharmacy Among Adults in Jazan Region, Saudi Arabia
title_short	Utilization of Psychotropic Medications and Polypharmacy Among Adults in Jazan Region, Saudi Arabia
title_full	Utilization of Psychotropic Medications and Polypharmacy Among Adults in Jazan Region, Saudi Arabia
title_fullStr	Utilization of Psychotropic Medications and Polypharmacy Among Adults in Jazan Region, Saudi Arabia
title_full_unstemmed	Utilization of Psychotropic Medications and Polypharmacy Among Adults in Jazan Region, Saudi Arabia
title_sort	utilization of psychotropic medications and polypharmacy among adults in jazan region, saudi arabia
publisher	Universitas Gadjah Mada
publishDate	2020
url	https://doaj.org/article/84079429b6094795a6abe4aaf546d915
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Utilization of Psychotropic Medications and Polypharmacy Among Adults in Jazan Region, Saudi Arabia

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