Shutdown of HIV-1 Transcription in T Cells by Nullbasic, a Mutant Tat Protein
ABSTRACT Nullbasic is a derivative of the HIV-1 transactivator of transcription (Tat) protein that strongly inhibits HIV-1 replication in lymphocytes. Here we show that lentiviral vectors that constitutively express a Nullbasic-ZsGreen1 (NB-ZSG1) fusion protein by the eEF1α promoter led to robust lo...
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Main Authors: | , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2016
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Subjects: | |
Online Access: | https://doaj.org/article/84093b2e09a64b72a2773d3f66c2ba85 |
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