Shutdown of HIV-1 Transcription in T Cells by Nullbasic, a Mutant Tat Protein

ABSTRACT Nullbasic is a derivative of the HIV-1 transactivator of transcription (Tat) protein that strongly inhibits HIV-1 replication in lymphocytes. Here we show that lentiviral vectors that constitutively express a Nullbasic-ZsGreen1 (NB-ZSG1) fusion protein by the eEF1α promoter led to robust lo...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Hongping Jin, Dongsheng Li, Haran Sivakumaran, Mary Lor, Lina Rustanti, Nicole Cloonan, Shivangi Wani, David Harrich
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://doaj.org/article/84093b2e09a64b72a2773d3f66c2ba85
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares