Shutdown of HIV-1 Transcription in T Cells by Nullbasic, a Mutant Tat Protein
ABSTRACT Nullbasic is a derivative of the HIV-1 transactivator of transcription (Tat) protein that strongly inhibits HIV-1 replication in lymphocytes. Here we show that lentiviral vectors that constitutively express a Nullbasic-ZsGreen1 (NB-ZSG1) fusion protein by the eEF1α promoter led to robust lo...
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| Auteurs principaux: | , , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2016
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| Accès en ligne: | https://doaj.org/article/84093b2e09a64b72a2773d3f66c2ba85 |
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