Active maintenance of proton motive force mediates starvation-induced bacterial antibiotic tolerance in Escherichia coli

The proton motive force (PMF) is a critical electrochemical gradient involved in bacterial energy metabolism. Here, Miaomiao Wang, Edward Wai Chi Chan et al. demonstrate that the PMF plays a key role in starvation-induced antibiotic tolerance in E. coli, suggesting that PMF disruption could be a fut...

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Autores principales:	Miaomiao Wang, Edward Wai Chi Chan, Yingkun Wan, Marcus Ho-yin Wong, Sheng Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/8414b54986c941f29ad265435e846442
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spelling	oai:doaj.org-article:8414b54986c941f29ad265435e8464422021-12-02T17:24:11ZActive maintenance of proton motive force mediates starvation-induced bacterial antibiotic tolerance in Escherichia coli10.1038/s42003-021-02612-12399-3642https://doaj.org/article/8414b54986c941f29ad265435e8464422021-09-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02612-1https://doaj.org/toc/2399-3642The proton motive force (PMF) is a critical electrochemical gradient involved in bacterial energy metabolism. Here, Miaomiao Wang, Edward Wai Chi Chan et al. demonstrate that the PMF plays a key role in starvation-induced antibiotic tolerance in E. coli, suggesting that PMF disruption could be a future strategy to treat bacterial infection.Miaomiao WangEdward Wai Chi ChanYingkun WanMarcus Ho-yin WongSheng ChenNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Miaomiao Wang Edward Wai Chi Chan Yingkun Wan Marcus Ho-yin Wong Sheng Chen Active maintenance of proton motive force mediates starvation-induced bacterial antibiotic tolerance in Escherichia coli
description	The proton motive force (PMF) is a critical electrochemical gradient involved in bacterial energy metabolism. Here, Miaomiao Wang, Edward Wai Chi Chan et al. demonstrate that the PMF plays a key role in starvation-induced antibiotic tolerance in E. coli, suggesting that PMF disruption could be a future strategy to treat bacterial infection.
format	article
author	Miaomiao Wang Edward Wai Chi Chan Yingkun Wan Marcus Ho-yin Wong Sheng Chen
author_facet	Miaomiao Wang Edward Wai Chi Chan Yingkun Wan Marcus Ho-yin Wong Sheng Chen
author_sort	Miaomiao Wang
title	Active maintenance of proton motive force mediates starvation-induced bacterial antibiotic tolerance in Escherichia coli
title_short	Active maintenance of proton motive force mediates starvation-induced bacterial antibiotic tolerance in Escherichia coli
title_full	Active maintenance of proton motive force mediates starvation-induced bacterial antibiotic tolerance in Escherichia coli
title_fullStr	Active maintenance of proton motive force mediates starvation-induced bacterial antibiotic tolerance in Escherichia coli
title_full_unstemmed	Active maintenance of proton motive force mediates starvation-induced bacterial antibiotic tolerance in Escherichia coli
title_sort	active maintenance of proton motive force mediates starvation-induced bacterial antibiotic tolerance in escherichia coli
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/8414b54986c941f29ad265435e846442
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Active maintenance of proton motive force mediates starvation-induced bacterial antibiotic tolerance in Escherichia coli

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