Treatment of Heart Failure with Sodium-Glucose Cotransporter 2 Inhibitors and Other Anti-diabetic Drugs
Patients with type 2 diabetes are at increased risk of developing heart failure, cardiovascular death and renal failure. The recent results of three large sodium-glucose cotransporter 2 inhibitor cardiovascular outcomes trials have demonstrated a reduction in heart failure hospitalisation and progre...
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Radcliffe Medical Media
2019
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oai:doaj.org-article:841865a83ad748579e673a5628ea7f0f2021-12-04T16:00:49ZTreatment of Heart Failure with Sodium-Glucose Cotransporter 2 Inhibitors and Other Anti-diabetic Drugs10.15420/cfr.2018.44.12057-75592057-7540https://doaj.org/article/841865a83ad748579e673a5628ea7f0f2019-01-01T00:00:00Zhttps://www.cfrjournal.com/articles/HF-Inhibitors-diabetichttps://doaj.org/toc/2057-7540https://doaj.org/toc/2057-7559Patients with type 2 diabetes are at increased risk of developing heart failure, cardiovascular death and renal failure. The recent results of three large sodium-glucose cotransporter 2 inhibitor cardiovascular outcomes trials have demonstrated a reduction in heart failure hospitalisation and progressive renal failure. One trial also showed a fall in cardiovascular and total death. A broad spectrum of patients with diabetes benefit from these salutary effects in cardiac and renal function and so these trials have important implications for the management of patients with type 2 diabetes. Selected glucagon-like peptide 1 receptor agonists have also been shown to reduce adverse cardiovascular outcomes.Thomas A ZelnikerEugene BraunwaldRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENCardiac Failure Review , Vol 5, Iss 1, Pp 27-30 (2019) |
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Diseases of the circulatory (Cardiovascular) system RC666-701 |
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Diseases of the circulatory (Cardiovascular) system RC666-701 Thomas A Zelniker Eugene Braunwald Treatment of Heart Failure with Sodium-Glucose Cotransporter 2 Inhibitors and Other Anti-diabetic Drugs |
description |
Patients with type 2 diabetes are at increased risk of developing heart failure, cardiovascular death and renal failure. The recent results of three large sodium-glucose cotransporter 2 inhibitor cardiovascular outcomes trials have demonstrated a reduction in heart failure hospitalisation and progressive renal failure. One trial also showed a fall in cardiovascular and total death. A broad spectrum of patients with diabetes benefit from these salutary effects in cardiac and renal function and so these trials have important implications for the management of patients with type 2 diabetes. Selected glucagon-like peptide 1 receptor agonists have also been shown to reduce adverse cardiovascular outcomes. |
format |
article |
author |
Thomas A Zelniker Eugene Braunwald |
author_facet |
Thomas A Zelniker Eugene Braunwald |
author_sort |
Thomas A Zelniker |
title |
Treatment of Heart Failure with Sodium-Glucose Cotransporter 2 Inhibitors and Other Anti-diabetic Drugs |
title_short |
Treatment of Heart Failure with Sodium-Glucose Cotransporter 2 Inhibitors and Other Anti-diabetic Drugs |
title_full |
Treatment of Heart Failure with Sodium-Glucose Cotransporter 2 Inhibitors and Other Anti-diabetic Drugs |
title_fullStr |
Treatment of Heart Failure with Sodium-Glucose Cotransporter 2 Inhibitors and Other Anti-diabetic Drugs |
title_full_unstemmed |
Treatment of Heart Failure with Sodium-Glucose Cotransporter 2 Inhibitors and Other Anti-diabetic Drugs |
title_sort |
treatment of heart failure with sodium-glucose cotransporter 2 inhibitors and other anti-diabetic drugs |
publisher |
Radcliffe Medical Media |
publishDate |
2019 |
url |
https://doaj.org/article/841865a83ad748579e673a5628ea7f0f |
work_keys_str_mv |
AT thomasazelniker treatmentofheartfailurewithsodiumglucosecotransporter2inhibitorsandotherantidiabeticdrugs AT eugenebraunwald treatmentofheartfailurewithsodiumglucosecotransporter2inhibitorsandotherantidiabeticdrugs |
_version_ |
1718372804860051456 |