Treatment of Heart Failure with Sodium-Glucose Cotransporter 2 Inhibitors and Other Anti-diabetic Drugs

Patients with type 2 diabetes are at increased risk of developing heart failure, cardiovascular death and renal failure. The recent results of three large sodium-glucose cotransporter 2 inhibitor cardiovascular outcomes trials have demonstrated a reduction in heart failure hospitalisation and progre...

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Autores principales: Thomas A Zelniker, Eugene Braunwald
Formato: article
Lenguaje:EN
Publicado: Radcliffe Medical Media 2019
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Acceso en línea:https://doaj.org/article/841865a83ad748579e673a5628ea7f0f
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spelling oai:doaj.org-article:841865a83ad748579e673a5628ea7f0f2021-12-04T16:00:49ZTreatment of Heart Failure with Sodium-Glucose Cotransporter 2 Inhibitors and Other Anti-diabetic Drugs10.15420/cfr.2018.44.12057-75592057-7540https://doaj.org/article/841865a83ad748579e673a5628ea7f0f2019-01-01T00:00:00Zhttps://www.cfrjournal.com/articles/HF-Inhibitors-diabetichttps://doaj.org/toc/2057-7540https://doaj.org/toc/2057-7559Patients with type 2 diabetes are at increased risk of developing heart failure, cardiovascular death and renal failure. The recent results of three large sodium-glucose cotransporter 2 inhibitor cardiovascular outcomes trials have demonstrated a reduction in heart failure hospitalisation and progressive renal failure. One trial also showed a fall in cardiovascular and total death. A broad spectrum of patients with diabetes benefit from these salutary effects in cardiac and renal function and so these trials have important implications for the management of patients with type 2 diabetes. Selected glucagon-like peptide 1 receptor agonists have also been shown to reduce adverse cardiovascular outcomes.Thomas A ZelnikerEugene BraunwaldRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENCardiac Failure Review , Vol 5, Iss 1, Pp 27-30 (2019)
institution DOAJ
collection DOAJ
language EN
topic Diseases of the circulatory (Cardiovascular) system
RC666-701
spellingShingle Diseases of the circulatory (Cardiovascular) system
RC666-701
Thomas A Zelniker
Eugene Braunwald
Treatment of Heart Failure with Sodium-Glucose Cotransporter 2 Inhibitors and Other Anti-diabetic Drugs
description Patients with type 2 diabetes are at increased risk of developing heart failure, cardiovascular death and renal failure. The recent results of three large sodium-glucose cotransporter 2 inhibitor cardiovascular outcomes trials have demonstrated a reduction in heart failure hospitalisation and progressive renal failure. One trial also showed a fall in cardiovascular and total death. A broad spectrum of patients with diabetes benefit from these salutary effects in cardiac and renal function and so these trials have important implications for the management of patients with type 2 diabetes. Selected glucagon-like peptide 1 receptor agonists have also been shown to reduce adverse cardiovascular outcomes.
format article
author Thomas A Zelniker
Eugene Braunwald
author_facet Thomas A Zelniker
Eugene Braunwald
author_sort Thomas A Zelniker
title Treatment of Heart Failure with Sodium-Glucose Cotransporter 2 Inhibitors and Other Anti-diabetic Drugs
title_short Treatment of Heart Failure with Sodium-Glucose Cotransporter 2 Inhibitors and Other Anti-diabetic Drugs
title_full Treatment of Heart Failure with Sodium-Glucose Cotransporter 2 Inhibitors and Other Anti-diabetic Drugs
title_fullStr Treatment of Heart Failure with Sodium-Glucose Cotransporter 2 Inhibitors and Other Anti-diabetic Drugs
title_full_unstemmed Treatment of Heart Failure with Sodium-Glucose Cotransporter 2 Inhibitors and Other Anti-diabetic Drugs
title_sort treatment of heart failure with sodium-glucose cotransporter 2 inhibitors and other anti-diabetic drugs
publisher Radcliffe Medical Media
publishDate 2019
url https://doaj.org/article/841865a83ad748579e673a5628ea7f0f
work_keys_str_mv AT thomasazelniker treatmentofheartfailurewithsodiumglucosecotransporter2inhibitorsandotherantidiabeticdrugs
AT eugenebraunwald treatmentofheartfailurewithsodiumglucosecotransporter2inhibitorsandotherantidiabeticdrugs
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