Proteogenomic landscape of squamous cell lung cancer

Proteogenomic landscape of squamous cell lung cancer

Squamous cell lung cancer has dismal prognosis due to the dearth of effective treatments. Here, the authors perform an integrated proteogenomic analysis of the disease, revealing three proteomics-based subtypes and suggesting potential therapeutic opportunities.

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Auteurs principaux: Paul A. Stewart, Eric A. Welsh, Robbert J. C. Slebos, Bin Fang, Victoria Izumi, Matthew Chambers, Guolin Zhang, Ling Cen, Fredrik Pettersson, Yonghong Zhang, Zhihua Chen, Chia-Ho Cheng, Ram Thapa, Zachary Thompson, Katherine M. Fellows, Jewel M. Francis, James J. Saller, Tania Mesa, Chaomei Zhang, Sean Yoder, Gina M. DeNicola, Amer A. Beg, Theresa A. Boyle, Jamie K. Teer, Yian Ann Chen, John M. Koomen, Steven A. Eschrich, Eric B. Haura
Format: article
Langue:EN
Publié: Nature Portfolio 2019
Sujets:
Science
Q
Accès en ligne:https://doaj.org/article/841bd6d6165d4e9f8532ae0a3ce6a908
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Résumé:Squamous cell lung cancer has dismal prognosis due to the dearth of effective treatments. Here, the authors perform an integrated proteogenomic analysis of the disease, revealing three proteomics-based subtypes and suggesting potential therapeutic opportunities.

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