Proteogenomic landscape of squamous cell lung cancer
Squamous cell lung cancer has dismal prognosis due to the dearth of effective treatments. Here, the authors perform an integrated proteogenomic analysis of the disease, revealing three proteomics-based subtypes and suggesting potential therapeutic opportunities.
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Nature Portfolio
2019
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oai:doaj.org-article:841bd6d6165d4e9f8532ae0a3ce6a9082021-12-02T16:57:09ZProteogenomic landscape of squamous cell lung cancer10.1038/s41467-019-11452-x2041-1723https://doaj.org/article/841bd6d6165d4e9f8532ae0a3ce6a9082019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11452-xhttps://doaj.org/toc/2041-1723Squamous cell lung cancer has dismal prognosis due to the dearth of effective treatments. Here, the authors perform an integrated proteogenomic analysis of the disease, revealing three proteomics-based subtypes and suggesting potential therapeutic opportunities.Paul A. StewartEric A. WelshRobbert J. C. SlebosBin FangVictoria IzumiMatthew ChambersGuolin ZhangLing CenFredrik PetterssonYonghong ZhangZhihua ChenChia-Ho ChengRam ThapaZachary ThompsonKatherine M. FellowsJewel M. FrancisJames J. SallerTania MesaChaomei ZhangSean YoderGina M. DeNicolaAmer A. BegTheresa A. BoyleJamie K. TeerYian Ann ChenJohn M. KoomenSteven A. EschrichEric B. HauraNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Paul A. Stewart Eric A. Welsh Robbert J. C. Slebos Bin Fang Victoria Izumi Matthew Chambers Guolin Zhang Ling Cen Fredrik Pettersson Yonghong Zhang Zhihua Chen Chia-Ho Cheng Ram Thapa Zachary Thompson Katherine M. Fellows Jewel M. Francis James J. Saller Tania Mesa Chaomei Zhang Sean Yoder Gina M. DeNicola Amer A. Beg Theresa A. Boyle Jamie K. Teer Yian Ann Chen John M. Koomen Steven A. Eschrich Eric B. Haura Proteogenomic landscape of squamous cell lung cancer |
| description |
Squamous cell lung cancer has dismal prognosis due to the dearth of effective treatments. Here, the authors perform an integrated proteogenomic analysis of the disease, revealing three proteomics-based subtypes and suggesting potential therapeutic opportunities. |
| format |
article |
| author |
Paul A. Stewart Eric A. Welsh Robbert J. C. Slebos Bin Fang Victoria Izumi Matthew Chambers Guolin Zhang Ling Cen Fredrik Pettersson Yonghong Zhang Zhihua Chen Chia-Ho Cheng Ram Thapa Zachary Thompson Katherine M. Fellows Jewel M. Francis James J. Saller Tania Mesa Chaomei Zhang Sean Yoder Gina M. DeNicola Amer A. Beg Theresa A. Boyle Jamie K. Teer Yian Ann Chen John M. Koomen Steven A. Eschrich Eric B. Haura |
| author_facet |
Paul A. Stewart Eric A. Welsh Robbert J. C. Slebos Bin Fang Victoria Izumi Matthew Chambers Guolin Zhang Ling Cen Fredrik Pettersson Yonghong Zhang Zhihua Chen Chia-Ho Cheng Ram Thapa Zachary Thompson Katherine M. Fellows Jewel M. Francis James J. Saller Tania Mesa Chaomei Zhang Sean Yoder Gina M. DeNicola Amer A. Beg Theresa A. Boyle Jamie K. Teer Yian Ann Chen John M. Koomen Steven A. Eschrich Eric B. Haura |
| author_sort |
Paul A. Stewart |
| title |
Proteogenomic landscape of squamous cell lung cancer |
| title_short |
Proteogenomic landscape of squamous cell lung cancer |
| title_full |
Proteogenomic landscape of squamous cell lung cancer |
| title_fullStr |
Proteogenomic landscape of squamous cell lung cancer |
| title_full_unstemmed |
Proteogenomic landscape of squamous cell lung cancer |
| title_sort |
proteogenomic landscape of squamous cell lung cancer |
| publisher |
Nature Portfolio |
| publishDate |
2019 |
| url |
https://doaj.org/article/841bd6d6165d4e9f8532ae0a3ce6a908 |
| work_keys_str_mv |
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| _version_ |
1718382633960865792 |