Design principles of the paradoxical feedback between pancreatic alpha and beta cells
Abstract Mammalian glucose homeostasis is controlled by the antagonistic hormones insulin and glucagon, secreted by pancreatic beta and alpha cells respectively. These two cell types are adjacently located in the islets of Langerhans and affect each others’ secretions in a paradoxical manner: while...
Guardado en:
Autores principales: | Immacolata Garzilli, Shalev Itzkovitz |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/842b91bfe3374bf2a79a625849f3eb22 |
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