A pocket-escaping design to prevent the common interference with near-infrared fluorescent probes in vivo

A pocket-escaping design to prevent the common interference with near-infrared fluorescent probes in vivo

Near-infrared fluorescent probes hold great potential for biomedical imaging but most bind to albumin, generating unspecific fluorescence. Here the authors identify the acceptor (A) group as responsible and design a new A group that avoids capture by albumin, and apply it to imaging liver fibrosis i...

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Autores principales: Panfei Xing, Yiming Niu, Ruoyu Mu, Zhenzhen Wang, Daping Xie, Huanling Li, Lei Dong, Chunming Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/8430a4d16b8049588eb2895c6e380f41
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spelling oai:doaj.org-article:8430a4d16b8049588eb2895c6e380f412021-12-02T17:31:55ZA pocket-escaping design to prevent the common interference with near-infrared fluorescent probes in vivo10.1038/s41467-020-15323-82041-1723https://doaj.org/article/8430a4d16b8049588eb2895c6e380f412020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15323-8https://doaj.org/toc/2041-1723Near-infrared fluorescent probes hold great potential for biomedical imaging but most bind to albumin, generating unspecific fluorescence. Here the authors identify the acceptor (A) group as responsible and design a new A group that avoids capture by albumin, and apply it to imaging liver fibrosis in vivo.Panfei XingYiming NiuRuoyu MuZhenzhen WangDaping XieHuanling LiLei DongChunming WangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Panfei Xing
Yiming Niu
Ruoyu Mu
Zhenzhen Wang
Daping Xie
Huanling Li
Lei Dong
Chunming Wang
A pocket-escaping design to prevent the common interference with near-infrared fluorescent probes in vivo
description Near-infrared fluorescent probes hold great potential for biomedical imaging but most bind to albumin, generating unspecific fluorescence. Here the authors identify the acceptor (A) group as responsible and design a new A group that avoids capture by albumin, and apply it to imaging liver fibrosis in vivo.
format article
author Panfei Xing
Yiming Niu
Ruoyu Mu
Zhenzhen Wang
Daping Xie
Huanling Li
Lei Dong
Chunming Wang
author_facet Panfei Xing
Yiming Niu
Ruoyu Mu
Zhenzhen Wang
Daping Xie
Huanling Li
Lei Dong
Chunming Wang
author_sort Panfei Xing
title A pocket-escaping design to prevent the common interference with near-infrared fluorescent probes in vivo
title_short A pocket-escaping design to prevent the common interference with near-infrared fluorescent probes in vivo
title_full A pocket-escaping design to prevent the common interference with near-infrared fluorescent probes in vivo
title_fullStr A pocket-escaping design to prevent the common interference with near-infrared fluorescent probes in vivo
title_full_unstemmed A pocket-escaping design to prevent the common interference with near-infrared fluorescent probes in vivo
title_sort pocket-escaping design to prevent the common interference with near-infrared fluorescent probes in vivo
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/8430a4d16b8049588eb2895c6e380f41
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