An automated Bayesian pipeline for rapid analysis of single-molecule binding data
Analysis of single-molecule binding assays still requires substantial manual user intervention. Here, the authors present a pipeline for rapid, automated analysis of co-localization single-molecule spectroscopy images, with a modular user interface that can be adjusted to a range of experimental con...
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Nature Portfolio
2019
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oai:doaj.org-article:843e839540ba4dd28ca6c75bbc68d5262021-12-02T14:38:40ZAn automated Bayesian pipeline for rapid analysis of single-molecule binding data10.1038/s41467-018-08045-52041-1723https://doaj.org/article/843e839540ba4dd28ca6c75bbc68d5262019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08045-5https://doaj.org/toc/2041-1723Analysis of single-molecule binding assays still requires substantial manual user intervention. Here, the authors present a pipeline for rapid, automated analysis of co-localization single-molecule spectroscopy images, with a modular user interface that can be adjusted to a range of experimental conditions.Carlas S. SmithKarina JouravlevaMaximiliaan HuismanSamson M. JollyPhillip D. ZamoreDavid GrunwaldNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019) |
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Science Q |
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Science Q Carlas S. Smith Karina Jouravleva Maximiliaan Huisman Samson M. Jolly Phillip D. Zamore David Grunwald An automated Bayesian pipeline for rapid analysis of single-molecule binding data |
description |
Analysis of single-molecule binding assays still requires substantial manual user intervention. Here, the authors present a pipeline for rapid, automated analysis of co-localization single-molecule spectroscopy images, with a modular user interface that can be adjusted to a range of experimental conditions. |
format |
article |
author |
Carlas S. Smith Karina Jouravleva Maximiliaan Huisman Samson M. Jolly Phillip D. Zamore David Grunwald |
author_facet |
Carlas S. Smith Karina Jouravleva Maximiliaan Huisman Samson M. Jolly Phillip D. Zamore David Grunwald |
author_sort |
Carlas S. Smith |
title |
An automated Bayesian pipeline for rapid analysis of single-molecule binding data |
title_short |
An automated Bayesian pipeline for rapid analysis of single-molecule binding data |
title_full |
An automated Bayesian pipeline for rapid analysis of single-molecule binding data |
title_fullStr |
An automated Bayesian pipeline for rapid analysis of single-molecule binding data |
title_full_unstemmed |
An automated Bayesian pipeline for rapid analysis of single-molecule binding data |
title_sort |
automated bayesian pipeline for rapid analysis of single-molecule binding data |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/843e839540ba4dd28ca6c75bbc68d526 |
work_keys_str_mv |
AT carlasssmith anautomatedbayesianpipelineforrapidanalysisofsinglemoleculebindingdata AT karinajouravleva anautomatedbayesianpipelineforrapidanalysisofsinglemoleculebindingdata AT maximiliaanhuisman anautomatedbayesianpipelineforrapidanalysisofsinglemoleculebindingdata AT samsonmjolly anautomatedbayesianpipelineforrapidanalysisofsinglemoleculebindingdata AT phillipdzamore anautomatedbayesianpipelineforrapidanalysisofsinglemoleculebindingdata AT davidgrunwald anautomatedbayesianpipelineforrapidanalysisofsinglemoleculebindingdata AT carlasssmith automatedbayesianpipelineforrapidanalysisofsinglemoleculebindingdata AT karinajouravleva automatedbayesianpipelineforrapidanalysisofsinglemoleculebindingdata AT maximiliaanhuisman automatedbayesianpipelineforrapidanalysisofsinglemoleculebindingdata AT samsonmjolly automatedbayesianpipelineforrapidanalysisofsinglemoleculebindingdata AT phillipdzamore automatedbayesianpipelineforrapidanalysisofsinglemoleculebindingdata AT davidgrunwald automatedbayesianpipelineforrapidanalysisofsinglemoleculebindingdata |
_version_ |
1718390904794906624 |