An automated Bayesian pipeline for rapid analysis of single-molecule binding data

Analysis of single-molecule binding assays still requires substantial manual user intervention. Here, the authors present a pipeline for rapid, automated analysis of co-localization single-molecule spectroscopy images, with a modular user interface that can be adjusted to a range of experimental con...

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Autores principales: Carlas S. Smith, Karina Jouravleva, Maximiliaan Huisman, Samson M. Jolly, Phillip D. Zamore, David Grunwald
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/843e839540ba4dd28ca6c75bbc68d526
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spelling oai:doaj.org-article:843e839540ba4dd28ca6c75bbc68d5262021-12-02T14:38:40ZAn automated Bayesian pipeline for rapid analysis of single-molecule binding data10.1038/s41467-018-08045-52041-1723https://doaj.org/article/843e839540ba4dd28ca6c75bbc68d5262019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08045-5https://doaj.org/toc/2041-1723Analysis of single-molecule binding assays still requires substantial manual user intervention. Here, the authors present a pipeline for rapid, automated analysis of co-localization single-molecule spectroscopy images, with a modular user interface that can be adjusted to a range of experimental conditions.Carlas S. SmithKarina JouravlevaMaximiliaan HuismanSamson M. JollyPhillip D. ZamoreDavid GrunwaldNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Carlas S. Smith
Karina Jouravleva
Maximiliaan Huisman
Samson M. Jolly
Phillip D. Zamore
David Grunwald
An automated Bayesian pipeline for rapid analysis of single-molecule binding data
description Analysis of single-molecule binding assays still requires substantial manual user intervention. Here, the authors present a pipeline for rapid, automated analysis of co-localization single-molecule spectroscopy images, with a modular user interface that can be adjusted to a range of experimental conditions.
format article
author Carlas S. Smith
Karina Jouravleva
Maximiliaan Huisman
Samson M. Jolly
Phillip D. Zamore
David Grunwald
author_facet Carlas S. Smith
Karina Jouravleva
Maximiliaan Huisman
Samson M. Jolly
Phillip D. Zamore
David Grunwald
author_sort Carlas S. Smith
title An automated Bayesian pipeline for rapid analysis of single-molecule binding data
title_short An automated Bayesian pipeline for rapid analysis of single-molecule binding data
title_full An automated Bayesian pipeline for rapid analysis of single-molecule binding data
title_fullStr An automated Bayesian pipeline for rapid analysis of single-molecule binding data
title_full_unstemmed An automated Bayesian pipeline for rapid analysis of single-molecule binding data
title_sort automated bayesian pipeline for rapid analysis of single-molecule binding data
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/843e839540ba4dd28ca6c75bbc68d526
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