Tbx5a lineage tracing shows cardiomyocyte plasticity during zebrafish heart regeneration

It is not clear if it is the embryonic origin or anatomical location of cardiomyocytes that restrict their contribution to zebrafish heart regeneration. Here, the authors show a plasticity of embryonic precursors following tbx5a fate mapping and that trabecular cardiomyocytes help to rebuild the cor...

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Autores principales: Héctor Sánchez-Iranzo, María Galardi-Castilla, Carolina Minguillón, Andrés Sanz-Morejón, Juan Manuel González-Rosa, Anastasia Felker, Alexander Ernst, Gabriela Guzmán-Martínez, Christian Mosimann, Nadia Mercader
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/844df0d27aca4aa6824a248623f81885
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spelling oai:doaj.org-article:844df0d27aca4aa6824a248623f818852021-12-02T15:34:06ZTbx5a lineage tracing shows cardiomyocyte plasticity during zebrafish heart regeneration10.1038/s41467-017-02650-62041-1723https://doaj.org/article/844df0d27aca4aa6824a248623f818852018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02650-6https://doaj.org/toc/2041-1723It is not clear if it is the embryonic origin or anatomical location of cardiomyocytes that restrict their contribution to zebrafish heart regeneration. Here, the authors show a plasticity of embryonic precursors following tbx5a fate mapping and that trabecular cardiomyocytes help to rebuild the cortical myocardium.Héctor Sánchez-IranzoMaría Galardi-CastillaCarolina MinguillónAndrés Sanz-MorejónJuan Manuel González-RosaAnastasia FelkerAlexander ErnstGabriela Guzmán-MartínezChristian MosimannNadia MercaderNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Héctor Sánchez-Iranzo
María Galardi-Castilla
Carolina Minguillón
Andrés Sanz-Morejón
Juan Manuel González-Rosa
Anastasia Felker
Alexander Ernst
Gabriela Guzmán-Martínez
Christian Mosimann
Nadia Mercader
Tbx5a lineage tracing shows cardiomyocyte plasticity during zebrafish heart regeneration
description It is not clear if it is the embryonic origin or anatomical location of cardiomyocytes that restrict their contribution to zebrafish heart regeneration. Here, the authors show a plasticity of embryonic precursors following tbx5a fate mapping and that trabecular cardiomyocytes help to rebuild the cortical myocardium.
format article
author Héctor Sánchez-Iranzo
María Galardi-Castilla
Carolina Minguillón
Andrés Sanz-Morejón
Juan Manuel González-Rosa
Anastasia Felker
Alexander Ernst
Gabriela Guzmán-Martínez
Christian Mosimann
Nadia Mercader
author_facet Héctor Sánchez-Iranzo
María Galardi-Castilla
Carolina Minguillón
Andrés Sanz-Morejón
Juan Manuel González-Rosa
Anastasia Felker
Alexander Ernst
Gabriela Guzmán-Martínez
Christian Mosimann
Nadia Mercader
author_sort Héctor Sánchez-Iranzo
title Tbx5a lineage tracing shows cardiomyocyte plasticity during zebrafish heart regeneration
title_short Tbx5a lineage tracing shows cardiomyocyte plasticity during zebrafish heart regeneration
title_full Tbx5a lineage tracing shows cardiomyocyte plasticity during zebrafish heart regeneration
title_fullStr Tbx5a lineage tracing shows cardiomyocyte plasticity during zebrafish heart regeneration
title_full_unstemmed Tbx5a lineage tracing shows cardiomyocyte plasticity during zebrafish heart regeneration
title_sort tbx5a lineage tracing shows cardiomyocyte plasticity during zebrafish heart regeneration
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/844df0d27aca4aa6824a248623f81885
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