An evaluation of community assessment tools (CATs) in predicting use of clinical interventions and severe outcomes during the A(H1N1)pdm09 pandemic.

During severe influenza pandemics healthcare demand can exceed clinical capacity to provide normal standards of care. Community Assessment Tools (CATs) could provide a framework for triage decisions for hospital referral and admission. CATs have been developed based on evidence that supports the rec...

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Autores principales: Malcolm G Semple, Puja R Myles, Karl G Nicholson, Wei Shen Lim, Robert C Read, Bruce L Taylor, Stephen J Brett, Peter J M Openshaw, Joanne E Enstone, James McMenamin, Barbara Bannister, Jonathan S Nguyen-Van-Tam
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Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/845326c6b47141f88c8a2c21d77f2c4c
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spelling oai:doaj.org-article:845326c6b47141f88c8a2c21d77f2c4c2021-11-18T08:54:30ZAn evaluation of community assessment tools (CATs) in predicting use of clinical interventions and severe outcomes during the A(H1N1)pdm09 pandemic.1932-620310.1371/journal.pone.0075384https://doaj.org/article/845326c6b47141f88c8a2c21d77f2c4c2013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24069409/?tool=EBIhttps://doaj.org/toc/1932-6203During severe influenza pandemics healthcare demand can exceed clinical capacity to provide normal standards of care. Community Assessment Tools (CATs) could provide a framework for triage decisions for hospital referral and admission. CATs have been developed based on evidence that supports the recognition of severe influenza and pneumonia in the community (including resource limited settings) for adults, children and infants, and serious feverish illness in children. CATs use six objective criteria and one subjective criterion, any one or more of which should prompt urgent referral and admission to hospital. A retrospective evaluation of the ability of CATs to predict use of hospital-based interventions and patient outcomes in a pandemic was made using the first recorded routine clinical assessment on or shortly after admission from 1520 unselected patients (800 female, 480 children <16 years) admitted with PCR confirmed A(H1N1)pdm09 infection (the FLU-CIN cohort). Outcome measures included: any use of supplemental oxygen; mechanical ventilation; intravenous antibiotics; length of stay; intensive or high dependency care; death; and "severe outcome" (combined: use of intensive or high dependency care or death during admission). Unadjusted and multivariable analyses were conducted for children (age <16 years) and adults. Each CATs criterion independently identified both use of clinical interventions that would in normal circumstances only be provided in hospital and patient outcome measures. "Peripheral oxygen saturation ≤ 92% breathing air, or being on oxygen" performed well in predicting use of resources and outcomes for both adults and children; supporting routine measurement of peripheral oxygen saturation when assessing severity of disease. In multivariable analyses the single subjective criterion in CATs "other cause for clinical concern" independently predicted death in children and in adults predicted length of stay, mechanical ventilation and "severe outcome"; supporting the role of clinical acumen as an important independent predictor of serious illness.Malcolm G SemplePuja R MylesKarl G NicholsonWei Shen LimRobert C ReadBruce L TaylorStephen J BrettPeter J M OpenshawJoanne E EnstoneJames McMenaminBarbara BannisterJonathan S Nguyen-Van-TamPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 9, p e75384 (2013)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Malcolm G Semple
Puja R Myles
Karl G Nicholson
Wei Shen Lim
Robert C Read
Bruce L Taylor
Stephen J Brett
Peter J M Openshaw
Joanne E Enstone
James McMenamin
Barbara Bannister
Jonathan S Nguyen-Van-Tam
An evaluation of community assessment tools (CATs) in predicting use of clinical interventions and severe outcomes during the A(H1N1)pdm09 pandemic.
description During severe influenza pandemics healthcare demand can exceed clinical capacity to provide normal standards of care. Community Assessment Tools (CATs) could provide a framework for triage decisions for hospital referral and admission. CATs have been developed based on evidence that supports the recognition of severe influenza and pneumonia in the community (including resource limited settings) for adults, children and infants, and serious feverish illness in children. CATs use six objective criteria and one subjective criterion, any one or more of which should prompt urgent referral and admission to hospital. A retrospective evaluation of the ability of CATs to predict use of hospital-based interventions and patient outcomes in a pandemic was made using the first recorded routine clinical assessment on or shortly after admission from 1520 unselected patients (800 female, 480 children <16 years) admitted with PCR confirmed A(H1N1)pdm09 infection (the FLU-CIN cohort). Outcome measures included: any use of supplemental oxygen; mechanical ventilation; intravenous antibiotics; length of stay; intensive or high dependency care; death; and "severe outcome" (combined: use of intensive or high dependency care or death during admission). Unadjusted and multivariable analyses were conducted for children (age <16 years) and adults. Each CATs criterion independently identified both use of clinical interventions that would in normal circumstances only be provided in hospital and patient outcome measures. "Peripheral oxygen saturation ≤ 92% breathing air, or being on oxygen" performed well in predicting use of resources and outcomes for both adults and children; supporting routine measurement of peripheral oxygen saturation when assessing severity of disease. In multivariable analyses the single subjective criterion in CATs "other cause for clinical concern" independently predicted death in children and in adults predicted length of stay, mechanical ventilation and "severe outcome"; supporting the role of clinical acumen as an important independent predictor of serious illness.
format article
author Malcolm G Semple
Puja R Myles
Karl G Nicholson
Wei Shen Lim
Robert C Read
Bruce L Taylor
Stephen J Brett
Peter J M Openshaw
Joanne E Enstone
James McMenamin
Barbara Bannister
Jonathan S Nguyen-Van-Tam
author_facet Malcolm G Semple
Puja R Myles
Karl G Nicholson
Wei Shen Lim
Robert C Read
Bruce L Taylor
Stephen J Brett
Peter J M Openshaw
Joanne E Enstone
James McMenamin
Barbara Bannister
Jonathan S Nguyen-Van-Tam
author_sort Malcolm G Semple
title An evaluation of community assessment tools (CATs) in predicting use of clinical interventions and severe outcomes during the A(H1N1)pdm09 pandemic.
title_short An evaluation of community assessment tools (CATs) in predicting use of clinical interventions and severe outcomes during the A(H1N1)pdm09 pandemic.
title_full An evaluation of community assessment tools (CATs) in predicting use of clinical interventions and severe outcomes during the A(H1N1)pdm09 pandemic.
title_fullStr An evaluation of community assessment tools (CATs) in predicting use of clinical interventions and severe outcomes during the A(H1N1)pdm09 pandemic.
title_full_unstemmed An evaluation of community assessment tools (CATs) in predicting use of clinical interventions and severe outcomes during the A(H1N1)pdm09 pandemic.
title_sort evaluation of community assessment tools (cats) in predicting use of clinical interventions and severe outcomes during the a(h1n1)pdm09 pandemic.
publisher Public Library of Science (PLoS)
publishDate 2013
url https://doaj.org/article/845326c6b47141f88c8a2c21d77f2c4c
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