Palladium concave nanocrystals with high-index facets accelerate ascorbate oxidation in cancer treatment
The therapeutic efficiency of ascorbate is limited by its slow autoxidation. Here, the authors show the application of concave-structured palladium nanocrystals for the treatment of colorectal cancer through the oxidation of ascorbate, enhancing the production of oxidative stresses specifically on c...
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Nature Portfolio
2018
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oai:doaj.org-article:845a165ecf944562a8374c43f5a519352021-12-02T15:33:44ZPalladium concave nanocrystals with high-index facets accelerate ascorbate oxidation in cancer treatment10.1038/s41467-018-07257-z2041-1723https://doaj.org/article/845a165ecf944562a8374c43f5a519352018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07257-zhttps://doaj.org/toc/2041-1723The therapeutic efficiency of ascorbate is limited by its slow autoxidation. Here, the authors show the application of concave-structured palladium nanocrystals for the treatment of colorectal cancer through the oxidation of ascorbate, enhancing the production of oxidative stresses specifically on cancer cells.Yu ChongXing DaiGe FangRenfei WuLin ZhaoXiaochuan MaXin TianSangyun LeeChao ZhangChunying ChenZhifang ChaiCuicui GeRuhong ZhouNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018) |
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Science Q Yu Chong Xing Dai Ge Fang Renfei Wu Lin Zhao Xiaochuan Ma Xin Tian Sangyun Lee Chao Zhang Chunying Chen Zhifang Chai Cuicui Ge Ruhong Zhou Palladium concave nanocrystals with high-index facets accelerate ascorbate oxidation in cancer treatment |
description |
The therapeutic efficiency of ascorbate is limited by its slow autoxidation. Here, the authors show the application of concave-structured palladium nanocrystals for the treatment of colorectal cancer through the oxidation of ascorbate, enhancing the production of oxidative stresses specifically on cancer cells. |
format |
article |
author |
Yu Chong Xing Dai Ge Fang Renfei Wu Lin Zhao Xiaochuan Ma Xin Tian Sangyun Lee Chao Zhang Chunying Chen Zhifang Chai Cuicui Ge Ruhong Zhou |
author_facet |
Yu Chong Xing Dai Ge Fang Renfei Wu Lin Zhao Xiaochuan Ma Xin Tian Sangyun Lee Chao Zhang Chunying Chen Zhifang Chai Cuicui Ge Ruhong Zhou |
author_sort |
Yu Chong |
title |
Palladium concave nanocrystals with high-index facets accelerate ascorbate oxidation in cancer treatment |
title_short |
Palladium concave nanocrystals with high-index facets accelerate ascorbate oxidation in cancer treatment |
title_full |
Palladium concave nanocrystals with high-index facets accelerate ascorbate oxidation in cancer treatment |
title_fullStr |
Palladium concave nanocrystals with high-index facets accelerate ascorbate oxidation in cancer treatment |
title_full_unstemmed |
Palladium concave nanocrystals with high-index facets accelerate ascorbate oxidation in cancer treatment |
title_sort |
palladium concave nanocrystals with high-index facets accelerate ascorbate oxidation in cancer treatment |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/845a165ecf944562a8374c43f5a51935 |
work_keys_str_mv |
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