Palladium concave nanocrystals with high-index facets accelerate ascorbate oxidation in cancer treatment

The therapeutic efficiency of ascorbate is limited by its slow autoxidation. Here, the authors show the application of concave-structured palladium nanocrystals for the treatment of colorectal cancer through the oxidation of ascorbate, enhancing the production of oxidative stresses specifically on c...

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Autores principales: Yu Chong, Xing Dai, Ge Fang, Renfei Wu, Lin Zhao, Xiaochuan Ma, Xin Tian, Sangyun Lee, Chao Zhang, Chunying Chen, Zhifang Chai, Cuicui Ge, Ruhong Zhou
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/845a165ecf944562a8374c43f5a51935
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spelling oai:doaj.org-article:845a165ecf944562a8374c43f5a519352021-12-02T15:33:44ZPalladium concave nanocrystals with high-index facets accelerate ascorbate oxidation in cancer treatment10.1038/s41467-018-07257-z2041-1723https://doaj.org/article/845a165ecf944562a8374c43f5a519352018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07257-zhttps://doaj.org/toc/2041-1723The therapeutic efficiency of ascorbate is limited by its slow autoxidation. Here, the authors show the application of concave-structured palladium nanocrystals for the treatment of colorectal cancer through the oxidation of ascorbate, enhancing the production of oxidative stresses specifically on cancer cells.Yu ChongXing DaiGe FangRenfei WuLin ZhaoXiaochuan MaXin TianSangyun LeeChao ZhangChunying ChenZhifang ChaiCuicui GeRuhong ZhouNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yu Chong
Xing Dai
Ge Fang
Renfei Wu
Lin Zhao
Xiaochuan Ma
Xin Tian
Sangyun Lee
Chao Zhang
Chunying Chen
Zhifang Chai
Cuicui Ge
Ruhong Zhou
Palladium concave nanocrystals with high-index facets accelerate ascorbate oxidation in cancer treatment
description The therapeutic efficiency of ascorbate is limited by its slow autoxidation. Here, the authors show the application of concave-structured palladium nanocrystals for the treatment of colorectal cancer through the oxidation of ascorbate, enhancing the production of oxidative stresses specifically on cancer cells.
format article
author Yu Chong
Xing Dai
Ge Fang
Renfei Wu
Lin Zhao
Xiaochuan Ma
Xin Tian
Sangyun Lee
Chao Zhang
Chunying Chen
Zhifang Chai
Cuicui Ge
Ruhong Zhou
author_facet Yu Chong
Xing Dai
Ge Fang
Renfei Wu
Lin Zhao
Xiaochuan Ma
Xin Tian
Sangyun Lee
Chao Zhang
Chunying Chen
Zhifang Chai
Cuicui Ge
Ruhong Zhou
author_sort Yu Chong
title Palladium concave nanocrystals with high-index facets accelerate ascorbate oxidation in cancer treatment
title_short Palladium concave nanocrystals with high-index facets accelerate ascorbate oxidation in cancer treatment
title_full Palladium concave nanocrystals with high-index facets accelerate ascorbate oxidation in cancer treatment
title_fullStr Palladium concave nanocrystals with high-index facets accelerate ascorbate oxidation in cancer treatment
title_full_unstemmed Palladium concave nanocrystals with high-index facets accelerate ascorbate oxidation in cancer treatment
title_sort palladium concave nanocrystals with high-index facets accelerate ascorbate oxidation in cancer treatment
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/845a165ecf944562a8374c43f5a51935
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