RETROSPECTIVE EVALUATION OF PATIENTS WITH LANGERHANS CELL HISTIOCYTOSIS FOLLOWED IN OUR CLINIC

Objective: Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder that can be especially seen in children and young adults. The clinical presentation of patients with LCH varies according to the sites of involvement. In about half of patients, the disease is limited to a single organ sys...

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Autores principales:	Mehmet Can Ugur, Sinem Namdaroglu, Oktay Bilgir, Cansu Atmaca Mutlu, Füsun Gediz
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Diseases of the blood and blood-forming organs RC633-647.5
Acceso en línea:	https://doaj.org/article/846014ba5b5945e6a8bbf73315f12edd
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spelling	oai:doaj.org-article:846014ba5b5945e6a8bbf73315f12edd2021-11-10T04:37:52ZRETROSPECTIVE EVALUATION OF PATIENTS WITH LANGERHANS CELL HISTIOCYTOSIS FOLLOWED IN OUR CLINIC2531-137910.1016/j.htct.2021.10.1061https://doaj.org/article/846014ba5b5945e6a8bbf73315f12edd2021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2531137921012086https://doaj.org/toc/2531-1379Objective: Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder that can be especially seen in children and young adults. The clinical presentation of patients with LCH varies according to the sites of involvement. In about half of patients, the disease is limited to a single organ system and bone involvement is very common. In this study, it was aimed to retrospectively evaluation the patients diagnosed with LCH who were followed up and treated in our clinic. Methodology: The data of patients over the age of 18 years who were followed up and treated in Bozyaka Training and Research Hospital Hematology Clinic between 2015-2021 were scanned retrospectively from the hospital system. Results: Data of 6 patients were obtained. The mean age of the patients was 33.6. There was no difference between the genders. Pain was the reason for admission in 4 patients and was the most common symptom. While the most frequently involved system was the skeletal system with 5 patients, lung involvement was seen in 2 patients. Vinblastine and prednisolone combination therapy was given to 1 patient, who developed steroid-related avascular necrosis. One patient who was planned for combination treatment Conclusion: LCH is a rare disease especially seen in children and young adults. It can involve the skeletal system, lungs, and other organs. The prognosis is often good with excision of the lesion or systemic treatment.Mehmet Can UgurSinem NamdarogluOktay BilgirCansu Atmaca MutluFüsun GedizElsevierarticleDiseases of the blood and blood-forming organsRC633-647.5ENHematology, Transfusion and Cell Therapy, Vol 43, Iss , Pp S51-S52 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the blood and blood-forming organs RC633-647.5
spellingShingle	Diseases of the blood and blood-forming organs RC633-647.5 Mehmet Can Ugur Sinem Namdaroglu Oktay Bilgir Cansu Atmaca Mutlu Füsun Gediz RETROSPECTIVE EVALUATION OF PATIENTS WITH LANGERHANS CELL HISTIOCYTOSIS FOLLOWED IN OUR CLINIC
description	Objective: Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder that can be especially seen in children and young adults. The clinical presentation of patients with LCH varies according to the sites of involvement. In about half of patients, the disease is limited to a single organ system and bone involvement is very common. In this study, it was aimed to retrospectively evaluation the patients diagnosed with LCH who were followed up and treated in our clinic. Methodology: The data of patients over the age of 18 years who were followed up and treated in Bozyaka Training and Research Hospital Hematology Clinic between 2015-2021 were scanned retrospectively from the hospital system. Results: Data of 6 patients were obtained. The mean age of the patients was 33.6. There was no difference between the genders. Pain was the reason for admission in 4 patients and was the most common symptom. While the most frequently involved system was the skeletal system with 5 patients, lung involvement was seen in 2 patients. Vinblastine and prednisolone combination therapy was given to 1 patient, who developed steroid-related avascular necrosis. One patient who was planned for combination treatment Conclusion: LCH is a rare disease especially seen in children and young adults. It can involve the skeletal system, lungs, and other organs. The prognosis is often good with excision of the lesion or systemic treatment.
format	article
author	Mehmet Can Ugur Sinem Namdaroglu Oktay Bilgir Cansu Atmaca Mutlu Füsun Gediz
author_facet	Mehmet Can Ugur Sinem Namdaroglu Oktay Bilgir Cansu Atmaca Mutlu Füsun Gediz
author_sort	Mehmet Can Ugur
title	RETROSPECTIVE EVALUATION OF PATIENTS WITH LANGERHANS CELL HISTIOCYTOSIS FOLLOWED IN OUR CLINIC
title_short	RETROSPECTIVE EVALUATION OF PATIENTS WITH LANGERHANS CELL HISTIOCYTOSIS FOLLOWED IN OUR CLINIC
title_full	RETROSPECTIVE EVALUATION OF PATIENTS WITH LANGERHANS CELL HISTIOCYTOSIS FOLLOWED IN OUR CLINIC
title_fullStr	RETROSPECTIVE EVALUATION OF PATIENTS WITH LANGERHANS CELL HISTIOCYTOSIS FOLLOWED IN OUR CLINIC
title_full_unstemmed	RETROSPECTIVE EVALUATION OF PATIENTS WITH LANGERHANS CELL HISTIOCYTOSIS FOLLOWED IN OUR CLINIC
title_sort	retrospective evaluation of patients with langerhans cell histiocytosis followed in our clinic
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/846014ba5b5945e6a8bbf73315f12edd
work_keys_str_mv	AT mehmetcanugur retrospectiveevaluationofpatientswithlangerhanscellhistiocytosisfollowedinourclinic AT sinemnamdaroglu retrospectiveevaluationofpatientswithlangerhanscellhistiocytosisfollowedinourclinic AT oktaybilgir retrospectiveevaluationofpatientswithlangerhanscellhistiocytosisfollowedinourclinic AT cansuatmacamutlu retrospectiveevaluationofpatientswithlangerhanscellhistiocytosisfollowedinourclinic AT fusungediz retrospectiveevaluationofpatientswithlangerhanscellhistiocytosisfollowedinourclinic
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RETROSPECTIVE EVALUATION OF PATIENTS WITH LANGERHANS CELL HISTIOCYTOSIS FOLLOWED IN OUR CLINIC

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