Functional screen of inflammatory bowel disease genes reveals key epithelial functions

Abstract Background Genetic studies have been tremendously successful in identifying genomic regions associated with a wide variety of phenotypes, although the success of these studies in identifying causal genes, their variants, and their functional impacts has been more limited. Methods We identif...

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Autores principales:	Jessy Carol Ntunzwenimana, Gabrielle Boucher, Jean Paquette, Hugues Gosselin, Azadeh Alikashani, Nicolas Morin, Claudine Beauchamp, Louise Thauvette, Marie-Ève Rivard, Frédérique Dupuis, Sonia Deschênes, Sylvain Foisy, Frédéric Latour, Geneviève Lavallée, Mark J. Daly, Ramnik J. Xavier, the iGenoMed Consortium, Guy Charron, Philippe Goyette, John D. Rioux
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Inflammatory bowel diseases Type I interferon response Mucosal immunity Secretory immunoglobulins Medicine R Genetics QH426-470
Acceso en línea:	https://doaj.org/article/8469a01eca954f73a71584a0462d259d
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Functional screen of inflammatory bowel disease genes reveals key epithelial functions

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