Prc1-rich kinetochores are required for error-free acentrosomal spindle bipolarization during meiosis I in mouse oocytes
Oocyte meiosis must achieve spindle bipolarization without predefined spatial cues. Yoshida et al. demonstrate that spindle bipolarization during meiosis I in mouse oocytes requires kinetochores to prevent chromosome segregation errors, a phenomenon that does not occur in error-prone human oocytes.
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Nature Portfolio
2020
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oai:doaj.org-article:846a65e485104228b1fc63d20e3f1d9c2021-12-02T14:47:36ZPrc1-rich kinetochores are required for error-free acentrosomal spindle bipolarization during meiosis I in mouse oocytes10.1038/s41467-020-16488-y2041-1723https://doaj.org/article/846a65e485104228b1fc63d20e3f1d9c2020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16488-yhttps://doaj.org/toc/2041-1723Oocyte meiosis must achieve spindle bipolarization without predefined spatial cues. Yoshida et al. demonstrate that spindle bipolarization during meiosis I in mouse oocytes requires kinetochores to prevent chromosome segregation errors, a phenomenon that does not occur in error-prone human oocytes.Shuhei YoshidaSui NishiyamaLisa ListerShu HashimotoTappei MishinaAurélien CourtoisHirohisa KyogokuTakaya AbeAki ShiraishiMeenakshi ChoudharyYoshiharu NakaokaMary HerbertTomoya S. KitajimaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020) |
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DOAJ |
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Science Q |
spellingShingle |
Science Q Shuhei Yoshida Sui Nishiyama Lisa Lister Shu Hashimoto Tappei Mishina Aurélien Courtois Hirohisa Kyogoku Takaya Abe Aki Shiraishi Meenakshi Choudhary Yoshiharu Nakaoka Mary Herbert Tomoya S. Kitajima Prc1-rich kinetochores are required for error-free acentrosomal spindle bipolarization during meiosis I in mouse oocytes |
description |
Oocyte meiosis must achieve spindle bipolarization without predefined spatial cues. Yoshida et al. demonstrate that spindle bipolarization during meiosis I in mouse oocytes requires kinetochores to prevent chromosome segregation errors, a phenomenon that does not occur in error-prone human oocytes. |
format |
article |
author |
Shuhei Yoshida Sui Nishiyama Lisa Lister Shu Hashimoto Tappei Mishina Aurélien Courtois Hirohisa Kyogoku Takaya Abe Aki Shiraishi Meenakshi Choudhary Yoshiharu Nakaoka Mary Herbert Tomoya S. Kitajima |
author_facet |
Shuhei Yoshida Sui Nishiyama Lisa Lister Shu Hashimoto Tappei Mishina Aurélien Courtois Hirohisa Kyogoku Takaya Abe Aki Shiraishi Meenakshi Choudhary Yoshiharu Nakaoka Mary Herbert Tomoya S. Kitajima |
author_sort |
Shuhei Yoshida |
title |
Prc1-rich kinetochores are required for error-free acentrosomal spindle bipolarization during meiosis I in mouse oocytes |
title_short |
Prc1-rich kinetochores are required for error-free acentrosomal spindle bipolarization during meiosis I in mouse oocytes |
title_full |
Prc1-rich kinetochores are required for error-free acentrosomal spindle bipolarization during meiosis I in mouse oocytes |
title_fullStr |
Prc1-rich kinetochores are required for error-free acentrosomal spindle bipolarization during meiosis I in mouse oocytes |
title_full_unstemmed |
Prc1-rich kinetochores are required for error-free acentrosomal spindle bipolarization during meiosis I in mouse oocytes |
title_sort |
prc1-rich kinetochores are required for error-free acentrosomal spindle bipolarization during meiosis i in mouse oocytes |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/846a65e485104228b1fc63d20e3f1d9c |
work_keys_str_mv |
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