Advanced technique of laser Doppler imaging for the diagnostics of intensity of peripheral microcirculation changes in patients with diffused liver diseases

It is known that changes in patients with diffuse liver disease at the vascular level are systemic in nature. Identification of these changes may help predict disease course, the possibility of the therapy revising. 60 patients with alcoholic liver cirrhosis, steatohepatitis mixed etiology, viral he...

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Autores principales:	T. D. Gelt, A. V. Borsukov
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2015
Materias:	laser doppler imaging diffuse liver diseases diagnostics Science Q
Acceso en línea:	https://doaj.org/article/846b3ca15f55400b83cd13652c890db7
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spelling	oai:doaj.org-article:846b3ca15f55400b83cd13652c890db72021-11-23T06:14:31ZAdvanced technique of laser Doppler imaging for the diagnostics of intensity of peripheral microcirculation changes in patients with diffused liver diseases2541-94202587-9596https://doaj.org/article/846b3ca15f55400b83cd13652c890db72015-02-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/3https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596It is known that changes in patients with diffuse liver disease at the vascular level are systemic in nature. Identification of these changes may help predict disease course, the possibility of the therapy revising. 60 patients with alcoholic liver cirrhosis, steatohepatitis mixed etiology, viral hepatitis "B" and "C" were examined to evaluate the possibility of non-invasive laser Doppler imaging (LDI) offorecasting the course of various forms of diffuse liver disease. Perfusion (P) c.u; in area of thenar and hypothenar of both hands were estimated by LDI. As a provocative test was applied extended cold test. Difference between initial perfusion and after cold test (AP) was analyzed (%) afterwards. ΔP < 10% was estimated as disturbance of reversibility of tissue microcirculation functional resources, that served as the basis for unfavourable forecasting with high possibility of decompensation development (it was typical of all patients with liver cirrhosis Child - Pugh C and 50% patients with liver cirrhosis Child - Pugh В). ΔP > 10%, pointed out at conservation of microcirculation in these patient and about favourable forecasting of the disease course and lower possibility of decompensation of disease during 12 month (it was typical of all patients with liver cirrhosis Child - Pugh A, steatohepatitis, viral hepatitis and 50% patients with liver cirrhosis Child - Pugh В)T. D. GeltA. V. BorsukovScientific Сentre for Family Health and Human Reproduction Problemsarticlelaser doppler imagingdiffuse liver diseasesdiagnosticsScienceQRUActa Biomedica Scientifica, Vol 0, Iss 1, Pp 11-17 (2015)
institution	DOAJ
collection	DOAJ
language	RU
topic	laser doppler imaging diffuse liver diseases diagnostics Science Q
spellingShingle	laser doppler imaging diffuse liver diseases diagnostics Science Q T. D. Gelt A. V. Borsukov Advanced technique of laser Doppler imaging for the diagnostics of intensity of peripheral microcirculation changes in patients with diffused liver diseases
description	It is known that changes in patients with diffuse liver disease at the vascular level are systemic in nature. Identification of these changes may help predict disease course, the possibility of the therapy revising. 60 patients with alcoholic liver cirrhosis, steatohepatitis mixed etiology, viral hepatitis "B" and "C" were examined to evaluate the possibility of non-invasive laser Doppler imaging (LDI) offorecasting the course of various forms of diffuse liver disease. Perfusion (P) c.u; in area of thenar and hypothenar of both hands were estimated by LDI. As a provocative test was applied extended cold test. Difference between initial perfusion and after cold test (AP) was analyzed (%) afterwards. ΔP < 10% was estimated as disturbance of reversibility of tissue microcirculation functional resources, that served as the basis for unfavourable forecasting with high possibility of decompensation development (it was typical of all patients with liver cirrhosis Child - Pugh C and 50% patients with liver cirrhosis Child - Pugh В). ΔP > 10%, pointed out at conservation of microcirculation in these patient and about favourable forecasting of the disease course and lower possibility of decompensation of disease during 12 month (it was typical of all patients with liver cirrhosis Child - Pugh A, steatohepatitis, viral hepatitis and 50% patients with liver cirrhosis Child - Pugh В)
format	article
author	T. D. Gelt A. V. Borsukov
author_facet	T. D. Gelt A. V. Borsukov
author_sort	T. D. Gelt
title	Advanced technique of laser Doppler imaging for the diagnostics of intensity of peripheral microcirculation changes in patients with diffused liver diseases
title_short	Advanced technique of laser Doppler imaging for the diagnostics of intensity of peripheral microcirculation changes in patients with diffused liver diseases
title_full	Advanced technique of laser Doppler imaging for the diagnostics of intensity of peripheral microcirculation changes in patients with diffused liver diseases
title_fullStr	Advanced technique of laser Doppler imaging for the diagnostics of intensity of peripheral microcirculation changes in patients with diffused liver diseases
title_full_unstemmed	Advanced technique of laser Doppler imaging for the diagnostics of intensity of peripheral microcirculation changes in patients with diffused liver diseases
title_sort	advanced technique of laser doppler imaging for the diagnostics of intensity of peripheral microcirculation changes in patients with diffused liver diseases
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2015
url	https://doaj.org/article/846b3ca15f55400b83cd13652c890db7
work_keys_str_mv	AT tdgelt advancedtechniqueoflaserdopplerimagingforthediagnosticsofintensityofperipheralmicrocirculationchangesinpatientswithdiffusedliverdiseases AT avborsukov advancedtechniqueoflaserdopplerimagingforthediagnosticsofintensityofperipheralmicrocirculationchangesinpatientswithdiffusedliverdiseases
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Advanced technique of laser Doppler imaging for the diagnostics of intensity of peripheral microcirculation changes in patients with diffused liver diseases

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