Mucociliary clearance and microbiota of the nasal passages, sinuses in patients with chronic rhinosinusitis associated with gastroesophageal reflux disease

The aim of our investigation was to estimate the mucociliary clearance (MC), the spectrum of bacterial communities discharged from the middle meatus and sinus aspirates in patients with chronic rhinosinusitis (CRS) associated with gastroesophageal reflux disease (GERD), patients with CRS without GER...

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Autores principales:	I. V. Temnikova, E. V. Onuchina, M. V. Subbotina
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2016
Materias:	gastroaesophageal reflux disease microbiota mucociliary clearance Science Q
Acceso en línea:	https://doaj.org/article/847a275324b74282ad52a5556a484475
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spelling	oai:doaj.org-article:847a275324b74282ad52a5556a4844752021-11-23T06:14:34ZMucociliary clearance and microbiota of the nasal passages, sinuses in patients with chronic rhinosinusitis associated with gastroesophageal reflux disease2541-94202587-959610.12737/article_590823a47345c8.15562147https://doaj.org/article/847a275324b74282ad52a5556a4844752016-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/192https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The aim of our investigation was to estimate the mucociliary clearance (MC), the spectrum of bacterial communities discharged from the middle meatus and sinus aspirates in patients with chronic rhinosinusitis (CRS) associated with gastroesophageal reflux disease (GERD), patients with CRS without GERD and healthy volunteers. The study included 30 patients with CRS and GERD, 34 patients without GERD аnd 30 healthy volunteers. Association with CRS and GERD was characterized by statistically significant slowing of MC and quantitative and qualitative changing of characteristics of the nasal mucosa microflora, but not of the paranasal sinuses. In the group of patients with CRS with GERD, MC amounted to 28.5 ± 4.7 min, in the group without GERD - 23.6 ± 2.7 min, in the healthy group - 5.8 ± 1 min. S. аureus (р = 0.009), E. mli (р = 0.029) and Candida albicans (р = 0.013) were detected in the mucosa of the middle meatus of patients with CRS and GERD more than in patients with CRS without GERD. No significant differences in the microflora of the paranasal sinus aspirate were revealed.I. V. TemnikovaE. V. OnuchinaM. V. SubbotinaScientific Сentre for Family Health and Human Reproduction Problemsarticlegastroaesophageal reflux diseasemicrobiotamucociliary clearanceScienceQRUActa Biomedica Scientifica, Vol 1, Iss 3(2), Pp 78-81 (2016)
institution	DOAJ
collection	DOAJ
language	RU
topic	gastroaesophageal reflux disease microbiota mucociliary clearance Science Q
spellingShingle	gastroaesophageal reflux disease microbiota mucociliary clearance Science Q I. V. Temnikova E. V. Onuchina M. V. Subbotina Mucociliary clearance and microbiota of the nasal passages, sinuses in patients with chronic rhinosinusitis associated with gastroesophageal reflux disease
description	The aim of our investigation was to estimate the mucociliary clearance (MC), the spectrum of bacterial communities discharged from the middle meatus and sinus aspirates in patients with chronic rhinosinusitis (CRS) associated with gastroesophageal reflux disease (GERD), patients with CRS without GERD and healthy volunteers. The study included 30 patients with CRS and GERD, 34 patients without GERD аnd 30 healthy volunteers. Association with CRS and GERD was characterized by statistically significant slowing of MC and quantitative and qualitative changing of characteristics of the nasal mucosa microflora, but not of the paranasal sinuses. In the group of patients with CRS with GERD, MC amounted to 28.5 ± 4.7 min, in the group without GERD - 23.6 ± 2.7 min, in the healthy group - 5.8 ± 1 min. S. аureus (р = 0.009), E. mli (р = 0.029) and Candida albicans (р = 0.013) were detected in the mucosa of the middle meatus of patients with CRS and GERD more than in patients with CRS without GERD. No significant differences in the microflora of the paranasal sinus aspirate were revealed.
format	article
author	I. V. Temnikova E. V. Onuchina M. V. Subbotina
author_facet	I. V. Temnikova E. V. Onuchina M. V. Subbotina
author_sort	I. V. Temnikova
title	Mucociliary clearance and microbiota of the nasal passages, sinuses in patients with chronic rhinosinusitis associated with gastroesophageal reflux disease
title_short	Mucociliary clearance and microbiota of the nasal passages, sinuses in patients with chronic rhinosinusitis associated with gastroesophageal reflux disease
title_full	Mucociliary clearance and microbiota of the nasal passages, sinuses in patients with chronic rhinosinusitis associated with gastroesophageal reflux disease
title_fullStr	Mucociliary clearance and microbiota of the nasal passages, sinuses in patients with chronic rhinosinusitis associated with gastroesophageal reflux disease
title_full_unstemmed	Mucociliary clearance and microbiota of the nasal passages, sinuses in patients with chronic rhinosinusitis associated with gastroesophageal reflux disease
title_sort	mucociliary clearance and microbiota of the nasal passages, sinuses in patients with chronic rhinosinusitis associated with gastroesophageal reflux disease
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2016
url	https://doaj.org/article/847a275324b74282ad52a5556a484475
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Mucociliary clearance and microbiota of the nasal passages, sinuses in patients with chronic rhinosinusitis associated with gastroesophageal reflux disease

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