Differential activation of Wnt-β-catenin pathway in triple negative breast cancer increases MMP7 in a PTEN dependent manner.

Differential activation of Wnt-β-catenin pathway in triple negative breast cancer increases MMP7 in a PTEN dependent manner.

Mutations of genes in tumor cells of Triple Negative subset of Breast Cancer (TNBC) deregulate pathways of signal transduction. The loss of tumor suppressor gene PTEN is the most common first event associated with basal-like subtype (Martins, De, Almendro, Gonen, and Park, 2012). Here we report for...

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Main Authors: Nandini Dey, Brandon Young, Mark Abramovitz, Mark Bouzyk, Benjamin Barwick, Pradip De, Brian Leyland-Jones
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
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Science
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Online Access:https://doaj.org/article/84842f9f6bf74d00ad5f257d39d26dd2
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