Genetic and physical interactions between Polη and Rev1 in response to UV-induced DNA damage in mammalian cells
Abstract In response to UV irradiation, translesion DNA synthesis (TLS) utilizes specialized DNA polymerases to bypass replication-blocking lesions. In a well-established polymerase switch model, Polη is thought to be a preferred TLS polymerase to insert correct nucleotides across from the thymine d...
Guardado en:
Autores principales: | Tonghui Bi, Xiaohong Niu, Chunping Qin, Wei Xiao |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/84893909b2c14fa98bd3f2f0eb8fa9cd |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Deficiency of Polη in Saccharomyces cerevisiae reveals the impact of transcription on damage-induced cohesion.
por: Pei-Shang Wu, et al.
Publicado: (2021) -
Polη O-GlcNAcylation governs genome integrity during translesion DNA synthesis
por: Xiaolu Ma, et al.
Publicado: (2017) -
UV Radiation in DNA Damage and Repair Involving DNA-Photolyases and Cryptochromes
por: Yuliya L. Vechtomova, et al.
Publicado: (2021) -
Pol α-primase dependent nuclear localization of the mammalian CST complex
por: Joseph M. Kelich, et al.
Publicado: (2021) -
Translesion activity of PrimPol on DNA with cisplatin and DNA–protein cross-links
por: Elizaveta O. Boldinova, et al.
Publicado: (2021)