Autophagy facilitates adaptation of budding yeast to respiratory growth by recycling serine for one-carbon metabolism

Autophagy is important during stress and development, but how the metabolites generated are used by the cell remains unclear. Here, the authors demonstrate that budding yeast require autophagy to provide serine for one-carbon metabolism during the switch from glycolytic to respiratory growth.

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Autores principales:	Alexander I. May, Mark Prescott, Yoshinori Ohsumi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/848e8d66c68843d58e4a913ad2620fea
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spelling	oai:doaj.org-article:848e8d66c68843d58e4a913ad2620fea2021-12-02T19:16:33ZAutophagy facilitates adaptation of budding yeast to respiratory growth by recycling serine for one-carbon metabolism10.1038/s41467-020-18805-x2041-1723https://doaj.org/article/848e8d66c68843d58e4a913ad2620fea2020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18805-xhttps://doaj.org/toc/2041-1723Autophagy is important during stress and development, but how the metabolites generated are used by the cell remains unclear. Here, the authors demonstrate that budding yeast require autophagy to provide serine for one-carbon metabolism during the switch from glycolytic to respiratory growth.Alexander I. MayMark PrescottYoshinori OhsumiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Alexander I. May Mark Prescott Yoshinori Ohsumi Autophagy facilitates adaptation of budding yeast to respiratory growth by recycling serine for one-carbon metabolism
description	Autophagy is important during stress and development, but how the metabolites generated are used by the cell remains unclear. Here, the authors demonstrate that budding yeast require autophagy to provide serine for one-carbon metabolism during the switch from glycolytic to respiratory growth.
format	article
author	Alexander I. May Mark Prescott Yoshinori Ohsumi
author_facet	Alexander I. May Mark Prescott Yoshinori Ohsumi
author_sort	Alexander I. May
title	Autophagy facilitates adaptation of budding yeast to respiratory growth by recycling serine for one-carbon metabolism
title_short	Autophagy facilitates adaptation of budding yeast to respiratory growth by recycling serine for one-carbon metabolism
title_full	Autophagy facilitates adaptation of budding yeast to respiratory growth by recycling serine for one-carbon metabolism
title_fullStr	Autophagy facilitates adaptation of budding yeast to respiratory growth by recycling serine for one-carbon metabolism
title_full_unstemmed	Autophagy facilitates adaptation of budding yeast to respiratory growth by recycling serine for one-carbon metabolism
title_sort	autophagy facilitates adaptation of budding yeast to respiratory growth by recycling serine for one-carbon metabolism
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/848e8d66c68843d58e4a913ad2620fea
work_keys_str_mv	AT alexanderimay autophagyfacilitatesadaptationofbuddingyeasttorespiratorygrowthbyrecyclingserineforonecarbonmetabolism AT markprescott autophagyfacilitatesadaptationofbuddingyeasttorespiratorygrowthbyrecyclingserineforonecarbonmetabolism AT yoshinoriohsumi autophagyfacilitatesadaptationofbuddingyeasttorespiratorygrowthbyrecyclingserineforonecarbonmetabolism
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Autophagy facilitates adaptation of budding yeast to respiratory growth by recycling serine for one-carbon metabolism

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