CHD4 slides nucleosomes by decoupling entry- and exit-side DNA translocation
Chromatin remodellers hydrolyse ATP to move nucleosomal DNA against histone octamers. Here, the authors use single-molecule assays to examine the mechanism of action of CHD4 remodeller, and provide evidence that CHD4 slides nucleosomes by decoupling entry- and exit-side DNA translocation.
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Auteurs principaux: | Yichen Zhong, Bishnu P. Paudel, Daniel P. Ryan, Jason K. K. Low, Charlotte Franck, Karishma Patel, Max J. Bedward, Mario Torrado, Richard J. Payne, Antoine M. van Oijen, Joel P. Mackay |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2020
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Sujets: | |
Accès en ligne: | https://doaj.org/article/848eae28baf44153b8dee9ed3f4508b7 |
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