Choindroitinase ABC I-mediated enhancement of oncolytic virus spread and anti tumor efficacy: a mathematical model.
Oncolytic viruses are genetically engineered viruses that are designed to kill cancer cells while doing minimal damage to normal healthy tissue. After being injected into a tumor, they infect cancer cells, multiply inside them, and when a cancer cell is killed they move on to spread and infect other...
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Main Authors: | Yangjin Kim, Hyun Geun Lee, Nina Dmitrieva, Junseok Kim, Balveen Kaur, Avner Friedman |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2014
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Online Access: | https://doaj.org/article/8497ce99686f4893a132d2fd9b39be4b |
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