Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles

Extracellular vesicles can carry many different types of biological cargo and have been investigated as a biomarker for cancer diagnosis. Here the authors develop a microfluidic platform for rapid and sensitive isolation of tumor-specific extracellular vesicles.

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Autores principales: Eduardo Reátegui, Kristan E. van der Vos, Charles P. Lai, Mahnaz Zeinali, Nadia A. Atai, Berent Aldikacti, Frederick P. Floyd, Aimal H. Khankhel, Vishal Thapar, Fred H. Hochberg, Lecia V. Sequist, Brian V. Nahed, Bob S. Carter, Mehmet Toner, Leonora Balaj, David T. Ting, Xandra O. Breakefield, Shannon L. Stott
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/849c53b9683c4d739bdab8480afd929d
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spelling oai:doaj.org-article:849c53b9683c4d739bdab8480afd929d2021-12-02T15:34:23ZEngineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles10.1038/s41467-017-02261-12041-1723https://doaj.org/article/849c53b9683c4d739bdab8480afd929d2018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02261-1https://doaj.org/toc/2041-1723Extracellular vesicles can carry many different types of biological cargo and have been investigated as a biomarker for cancer diagnosis. Here the authors develop a microfluidic platform for rapid and sensitive isolation of tumor-specific extracellular vesicles.Eduardo ReáteguiKristan E. van der VosCharles P. LaiMahnaz ZeinaliNadia A. AtaiBerent AldikactiFrederick P. FloydAimal H. KhankhelVishal ThaparFred H. HochbergLecia V. SequistBrian V. NahedBob S. CarterMehmet TonerLeonora BalajDavid T. TingXandra O. BreakefieldShannon L. StottNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Eduardo Reátegui
Kristan E. van der Vos
Charles P. Lai
Mahnaz Zeinali
Nadia A. Atai
Berent Aldikacti
Frederick P. Floyd
Aimal H. Khankhel
Vishal Thapar
Fred H. Hochberg
Lecia V. Sequist
Brian V. Nahed
Bob S. Carter
Mehmet Toner
Leonora Balaj
David T. Ting
Xandra O. Breakefield
Shannon L. Stott
Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles
description Extracellular vesicles can carry many different types of biological cargo and have been investigated as a biomarker for cancer diagnosis. Here the authors develop a microfluidic platform for rapid and sensitive isolation of tumor-specific extracellular vesicles.
format article
author Eduardo Reátegui
Kristan E. van der Vos
Charles P. Lai
Mahnaz Zeinali
Nadia A. Atai
Berent Aldikacti
Frederick P. Floyd
Aimal H. Khankhel
Vishal Thapar
Fred H. Hochberg
Lecia V. Sequist
Brian V. Nahed
Bob S. Carter
Mehmet Toner
Leonora Balaj
David T. Ting
Xandra O. Breakefield
Shannon L. Stott
author_facet Eduardo Reátegui
Kristan E. van der Vos
Charles P. Lai
Mahnaz Zeinali
Nadia A. Atai
Berent Aldikacti
Frederick P. Floyd
Aimal H. Khankhel
Vishal Thapar
Fred H. Hochberg
Lecia V. Sequist
Brian V. Nahed
Bob S. Carter
Mehmet Toner
Leonora Balaj
David T. Ting
Xandra O. Breakefield
Shannon L. Stott
author_sort Eduardo Reátegui
title Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles
title_short Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles
title_full Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles
title_fullStr Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles
title_full_unstemmed Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles
title_sort engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/849c53b9683c4d739bdab8480afd929d
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