A pulsatile release platform based on photo-induced imine-crosslinking hydrogel promotes scarless wound healing

Dysfunctional and disfiguring scars can result from aberrant wound repair. Here, the authors develop a wound dressing material based on an integrated photo-crosslinking strategy and a microcapsule platform with pulsatile release of TGF-β inhibitor to achieve spatiotemporal specificity for scarless w...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Jian Zhang, Yongjun Zheng, Jimmy Lee, Jieyu Hua, Shilong Li, Ananth Panchamukhi, Jiping Yue, Xuewen Gou, Zhaofan Xia, Linyong Zhu, Xiaoyang Wu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/849f5fb7a026401fac2fcd2cc68603a8
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:849f5fb7a026401fac2fcd2cc68603a8
record_format dspace
spelling oai:doaj.org-article:849f5fb7a026401fac2fcd2cc68603a82021-12-02T16:30:42ZA pulsatile release platform based on photo-induced imine-crosslinking hydrogel promotes scarless wound healing10.1038/s41467-021-21964-02041-1723https://doaj.org/article/849f5fb7a026401fac2fcd2cc68603a82021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21964-0https://doaj.org/toc/2041-1723Dysfunctional and disfiguring scars can result from aberrant wound repair. Here, the authors develop a wound dressing material based on an integrated photo-crosslinking strategy and a microcapsule platform with pulsatile release of TGF-β inhibitor to achieve spatiotemporal specificity for scarless wound repair.Jian ZhangYongjun ZhengJimmy LeeJieyu HuaShilong LiAnanth PanchamukhiJiping YueXuewen GouZhaofan XiaLinyong ZhuXiaoyang WuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jian Zhang
Yongjun Zheng
Jimmy Lee
Jieyu Hua
Shilong Li
Ananth Panchamukhi
Jiping Yue
Xuewen Gou
Zhaofan Xia
Linyong Zhu
Xiaoyang Wu
A pulsatile release platform based on photo-induced imine-crosslinking hydrogel promotes scarless wound healing
description Dysfunctional and disfiguring scars can result from aberrant wound repair. Here, the authors develop a wound dressing material based on an integrated photo-crosslinking strategy and a microcapsule platform with pulsatile release of TGF-β inhibitor to achieve spatiotemporal specificity for scarless wound repair.
format article
author Jian Zhang
Yongjun Zheng
Jimmy Lee
Jieyu Hua
Shilong Li
Ananth Panchamukhi
Jiping Yue
Xuewen Gou
Zhaofan Xia
Linyong Zhu
Xiaoyang Wu
author_facet Jian Zhang
Yongjun Zheng
Jimmy Lee
Jieyu Hua
Shilong Li
Ananth Panchamukhi
Jiping Yue
Xuewen Gou
Zhaofan Xia
Linyong Zhu
Xiaoyang Wu
author_sort Jian Zhang
title A pulsatile release platform based on photo-induced imine-crosslinking hydrogel promotes scarless wound healing
title_short A pulsatile release platform based on photo-induced imine-crosslinking hydrogel promotes scarless wound healing
title_full A pulsatile release platform based on photo-induced imine-crosslinking hydrogel promotes scarless wound healing
title_fullStr A pulsatile release platform based on photo-induced imine-crosslinking hydrogel promotes scarless wound healing
title_full_unstemmed A pulsatile release platform based on photo-induced imine-crosslinking hydrogel promotes scarless wound healing
title_sort pulsatile release platform based on photo-induced imine-crosslinking hydrogel promotes scarless wound healing
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/849f5fb7a026401fac2fcd2cc68603a8
work_keys_str_mv AT jianzhang apulsatilereleaseplatformbasedonphotoinducediminecrosslinkinghydrogelpromotesscarlesswoundhealing
AT yongjunzheng apulsatilereleaseplatformbasedonphotoinducediminecrosslinkinghydrogelpromotesscarlesswoundhealing
AT jimmylee apulsatilereleaseplatformbasedonphotoinducediminecrosslinkinghydrogelpromotesscarlesswoundhealing
AT jieyuhua apulsatilereleaseplatformbasedonphotoinducediminecrosslinkinghydrogelpromotesscarlesswoundhealing
AT shilongli apulsatilereleaseplatformbasedonphotoinducediminecrosslinkinghydrogelpromotesscarlesswoundhealing
AT ananthpanchamukhi apulsatilereleaseplatformbasedonphotoinducediminecrosslinkinghydrogelpromotesscarlesswoundhealing
AT jipingyue apulsatilereleaseplatformbasedonphotoinducediminecrosslinkinghydrogelpromotesscarlesswoundhealing
AT xuewengou apulsatilereleaseplatformbasedonphotoinducediminecrosslinkinghydrogelpromotesscarlesswoundhealing
AT zhaofanxia apulsatilereleaseplatformbasedonphotoinducediminecrosslinkinghydrogelpromotesscarlesswoundhealing
AT linyongzhu apulsatilereleaseplatformbasedonphotoinducediminecrosslinkinghydrogelpromotesscarlesswoundhealing
AT xiaoyangwu apulsatilereleaseplatformbasedonphotoinducediminecrosslinkinghydrogelpromotesscarlesswoundhealing
AT jianzhang pulsatilereleaseplatformbasedonphotoinducediminecrosslinkinghydrogelpromotesscarlesswoundhealing
AT yongjunzheng pulsatilereleaseplatformbasedonphotoinducediminecrosslinkinghydrogelpromotesscarlesswoundhealing
AT jimmylee pulsatilereleaseplatformbasedonphotoinducediminecrosslinkinghydrogelpromotesscarlesswoundhealing
AT jieyuhua pulsatilereleaseplatformbasedonphotoinducediminecrosslinkinghydrogelpromotesscarlesswoundhealing
AT shilongli pulsatilereleaseplatformbasedonphotoinducediminecrosslinkinghydrogelpromotesscarlesswoundhealing
AT ananthpanchamukhi pulsatilereleaseplatformbasedonphotoinducediminecrosslinkinghydrogelpromotesscarlesswoundhealing
AT jipingyue pulsatilereleaseplatformbasedonphotoinducediminecrosslinkinghydrogelpromotesscarlesswoundhealing
AT xuewengou pulsatilereleaseplatformbasedonphotoinducediminecrosslinkinghydrogelpromotesscarlesswoundhealing
AT zhaofanxia pulsatilereleaseplatformbasedonphotoinducediminecrosslinkinghydrogelpromotesscarlesswoundhealing
AT linyongzhu pulsatilereleaseplatformbasedonphotoinducediminecrosslinkinghydrogelpromotesscarlesswoundhealing
AT xiaoyangwu pulsatilereleaseplatformbasedonphotoinducediminecrosslinkinghydrogelpromotesscarlesswoundhealing
_version_ 1718383938912649216