Oxypeucedanin and isoimperatorin extracted from Prangos ferulacea (L.) Lindl protect PC12 pheochromocytoma cells from oxidative stress and apoptosis induced by doxorubicin

Background and purpose: Doxorubicin (DOX) as a chemotherapeutic agent has been widely used in the treatment of various types of cancer. However, DOX exerts a toxic effect on normal tissues such as the brain. Furanocoumarins reduce the risk of cardiovascular and brain diseases because of their antiox...

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Autores principales: Fereshteh Jalilian, Maryam Moieni-Arya, Leila Hosseinzadeh, Yalda Shokoohinia
Formato: article
Lenguaje:EN
Publicado: Wolters Kluwer Medknow Publications 2022
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Acceso en línea:https://doaj.org/article/84a1c8348c5b478ab8411333ecd6d04c
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