Optimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases
RNA crosslinking and proximity ligation methods are used to identify transcriptome-wide base pairing interactions. Here, the authors report PARIS2 (psoralen analysis of RNA interactions and structures 2), a method for RNA duplex determination in vivo with higher efficiency than the previous PARIS me...
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Nature Portfolio
2021
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oai:doaj.org-article:84b70984cb2f4a888c00803699c67bcd2021-12-02T18:28:38ZOptimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases10.1038/s41467-021-22552-y2041-1723https://doaj.org/article/84b70984cb2f4a888c00803699c67bcd2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22552-yhttps://doaj.org/toc/2041-1723RNA crosslinking and proximity ligation methods are used to identify transcriptome-wide base pairing interactions. Here, the authors report PARIS2 (psoralen analysis of RNA interactions and structures 2), a method for RNA duplex determination in vivo with higher efficiency than the previous PARIS method.Minjie ZhangKongpan LiJianhui BaiWillem A. VelemaChengqing YuRyan van DammeWilson H. LeeMaia L. CorpuzJian-Fu ChenZhipeng LuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021) |
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Science Q Minjie Zhang Kongpan Li Jianhui Bai Willem A. Velema Chengqing Yu Ryan van Damme Wilson H. Lee Maia L. Corpuz Jian-Fu Chen Zhipeng Lu Optimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases |
description |
RNA crosslinking and proximity ligation methods are used to identify transcriptome-wide base pairing interactions. Here, the authors report PARIS2 (psoralen analysis of RNA interactions and structures 2), a method for RNA duplex determination in vivo with higher efficiency than the previous PARIS method. |
format |
article |
author |
Minjie Zhang Kongpan Li Jianhui Bai Willem A. Velema Chengqing Yu Ryan van Damme Wilson H. Lee Maia L. Corpuz Jian-Fu Chen Zhipeng Lu |
author_facet |
Minjie Zhang Kongpan Li Jianhui Bai Willem A. Velema Chengqing Yu Ryan van Damme Wilson H. Lee Maia L. Corpuz Jian-Fu Chen Zhipeng Lu |
author_sort |
Minjie Zhang |
title |
Optimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases |
title_short |
Optimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases |
title_full |
Optimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases |
title_fullStr |
Optimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases |
title_full_unstemmed |
Optimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases |
title_sort |
optimized photochemistry enables efficient analysis of dynamic rna structuromes and interactomes in genetic and infectious diseases |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/84b70984cb2f4a888c00803699c67bcd |
work_keys_str_mv |
AT minjiezhang optimizedphotochemistryenablesefficientanalysisofdynamicrnastructuromesandinteractomesingeneticandinfectiousdiseases AT kongpanli optimizedphotochemistryenablesefficientanalysisofdynamicrnastructuromesandinteractomesingeneticandinfectiousdiseases AT jianhuibai optimizedphotochemistryenablesefficientanalysisofdynamicrnastructuromesandinteractomesingeneticandinfectiousdiseases AT willemavelema optimizedphotochemistryenablesefficientanalysisofdynamicrnastructuromesandinteractomesingeneticandinfectiousdiseases AT chengqingyu optimizedphotochemistryenablesefficientanalysisofdynamicrnastructuromesandinteractomesingeneticandinfectiousdiseases AT ryanvandamme optimizedphotochemistryenablesefficientanalysisofdynamicrnastructuromesandinteractomesingeneticandinfectiousdiseases AT wilsonhlee optimizedphotochemistryenablesefficientanalysisofdynamicrnastructuromesandinteractomesingeneticandinfectiousdiseases AT maialcorpuz optimizedphotochemistryenablesefficientanalysisofdynamicrnastructuromesandinteractomesingeneticandinfectiousdiseases AT jianfuchen optimizedphotochemistryenablesefficientanalysisofdynamicrnastructuromesandinteractomesingeneticandinfectiousdiseases AT zhipenglu optimizedphotochemistryenablesefficientanalysisofdynamicrnastructuromesandinteractomesingeneticandinfectiousdiseases |
_version_ |
1718377989695078400 |