Implication of thyroid function in periodontitis: a nationwide population-based study

Abstract Possible links between periodontitis and various cardiometabolic and autoimmune diseases have been advocated on the basis of chronic inflammation or oxidative stress. However, the association between periodontitis and thyroid dysfunction is under-researched. Participants without previous th...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Eyun Song, Min Jeong Park, Jung A. Kim, Eun Roh, Ji Hee Yu, Nam Hoon Kim, Hye Jin Yoo, Ji A. Seo, Sin Gon Kim, Nan Hee Kim, Sei Hyun Baik, Kyung Mook Choi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/84c31e516aa1418e9097ca6bf190cb11
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:84c31e516aa1418e9097ca6bf190cb11
record_format	dspace
spelling	oai:doaj.org-article:84c31e516aa1418e9097ca6bf190cb112021-11-14T12:17:50ZImplication of thyroid function in periodontitis: a nationwide population-based study10.1038/s41598-021-01682-92045-2322https://doaj.org/article/84c31e516aa1418e9097ca6bf190cb112021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-01682-9https://doaj.org/toc/2045-2322Abstract Possible links between periodontitis and various cardiometabolic and autoimmune diseases have been advocated on the basis of chronic inflammation or oxidative stress. However, the association between periodontitis and thyroid dysfunction is under-researched. Participants without previous thyroid disease or ongoing thyroid-related medication were included from a nationwide population-level survey. Participants were categorized into tertiles of thyroid stimulating hormone (TSH) levels (first tertile < 1.76 mIU/L; second tertile 1.76–2.83 mIU/L; third tertile > 2.83 mIU/L), and periodontal condition was assessed using the Community Periodontal Index. Of the total of 5468 participants, 1423 had periodontitis (26%). A significant difference in the weighted prevalence of periodontitis according to TSH tertiles was observed, with the highest prevalence in the first tertile (26.5%) and the lowest prevalence in the third tertile (20.9%, p = 0.003). Subjects in the first TSH tertile had higher odds for periodontitis than those in the third tertile (OR 1.36, 95% CI 1.10–1.68; p for trend = 0.005) after adjusting for covariates. This association was consistent across subgroups and within sensitivity analyses among subjects without specific factors affecting thyroid function or diseases reported to be related to periodontitis. The present study demonstrated that low TSH levels were associated with significantly higher odds for periodontitis.Eyun SongMin Jeong ParkJung A. KimEun RohJi Hee YuNam Hoon KimHye Jin YooJi A. SeoSin Gon KimNan Hee KimSei Hyun BaikKyung Mook ChoiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Eyun Song Min Jeong Park Jung A. Kim Eun Roh Ji Hee Yu Nam Hoon Kim Hye Jin Yoo Ji A. Seo Sin Gon Kim Nan Hee Kim Sei Hyun Baik Kyung Mook Choi Implication of thyroid function in periodontitis: a nationwide population-based study
description	Abstract Possible links between periodontitis and various cardiometabolic and autoimmune diseases have been advocated on the basis of chronic inflammation or oxidative stress. However, the association between periodontitis and thyroid dysfunction is under-researched. Participants without previous thyroid disease or ongoing thyroid-related medication were included from a nationwide population-level survey. Participants were categorized into tertiles of thyroid stimulating hormone (TSH) levels (first tertile < 1.76 mIU/L; second tertile 1.76–2.83 mIU/L; third tertile > 2.83 mIU/L), and periodontal condition was assessed using the Community Periodontal Index. Of the total of 5468 participants, 1423 had periodontitis (26%). A significant difference in the weighted prevalence of periodontitis according to TSH tertiles was observed, with the highest prevalence in the first tertile (26.5%) and the lowest prevalence in the third tertile (20.9%, p = 0.003). Subjects in the first TSH tertile had higher odds for periodontitis than those in the third tertile (OR 1.36, 95% CI 1.10–1.68; p for trend = 0.005) after adjusting for covariates. This association was consistent across subgroups and within sensitivity analyses among subjects without specific factors affecting thyroid function or diseases reported to be related to periodontitis. The present study demonstrated that low TSH levels were associated with significantly higher odds for periodontitis.
format	article
author	Eyun Song Min Jeong Park Jung A. Kim Eun Roh Ji Hee Yu Nam Hoon Kim Hye Jin Yoo Ji A. Seo Sin Gon Kim Nan Hee Kim Sei Hyun Baik Kyung Mook Choi
author_facet	Eyun Song Min Jeong Park Jung A. Kim Eun Roh Ji Hee Yu Nam Hoon Kim Hye Jin Yoo Ji A. Seo Sin Gon Kim Nan Hee Kim Sei Hyun Baik Kyung Mook Choi
author_sort	Eyun Song
title	Implication of thyroid function in periodontitis: a nationwide population-based study
title_short	Implication of thyroid function in periodontitis: a nationwide population-based study
title_full	Implication of thyroid function in periodontitis: a nationwide population-based study
title_fullStr	Implication of thyroid function in periodontitis: a nationwide population-based study
title_full_unstemmed	Implication of thyroid function in periodontitis: a nationwide population-based study
title_sort	implication of thyroid function in periodontitis: a nationwide population-based study
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/84c31e516aa1418e9097ca6bf190cb11
work_keys_str_mv	AT eyunsong implicationofthyroidfunctioninperiodontitisanationwidepopulationbasedstudy AT minjeongpark implicationofthyroidfunctioninperiodontitisanationwidepopulationbasedstudy AT jungakim implicationofthyroidfunctioninperiodontitisanationwidepopulationbasedstudy AT eunroh implicationofthyroidfunctioninperiodontitisanationwidepopulationbasedstudy AT jiheeyu implicationofthyroidfunctioninperiodontitisanationwidepopulationbasedstudy AT namhoonkim implicationofthyroidfunctioninperiodontitisanationwidepopulationbasedstudy AT hyejinyoo implicationofthyroidfunctioninperiodontitisanationwidepopulationbasedstudy AT jiaseo implicationofthyroidfunctioninperiodontitisanationwidepopulationbasedstudy AT singonkim implicationofthyroidfunctioninperiodontitisanationwidepopulationbasedstudy AT nanheekim implicationofthyroidfunctioninperiodontitisanationwidepopulationbasedstudy AT seihyunbaik implicationofthyroidfunctioninperiodontitisanationwidepopulationbasedstudy AT kyungmookchoi implicationofthyroidfunctioninperiodontitisanationwidepopulationbasedstudy
_version_	1718429297972084736

Implication of thyroid function in periodontitis: a nationwide population-based study

Ejemplares similares