Topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area
How corticostriatal connections of different pyramidal cell types are organized, particularly in convergent circuits, has not been evaluated in detail. Here, cell type-specific Cre-driver mice reveal that pyramidal tract-type corticostriatal projections, though broadly similar to intratelencephalic-...
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Nature Portfolio
2018
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oai:doaj.org-article:84c613a3ab84486487983e800ed1d0b32021-12-02T14:40:32ZTopographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area10.1038/s41467-018-05780-72041-1723https://doaj.org/article/84c613a3ab84486487983e800ed1d0b32018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05780-7https://doaj.org/toc/2041-1723How corticostriatal connections of different pyramidal cell types are organized, particularly in convergent circuits, has not been evaluated in detail. Here, cell type-specific Cre-driver mice reveal that pyramidal tract-type corticostriatal projections, though broadly similar to intratelencephalic-type projections from the same cortical region, are generally more restricted and variable in their topographic termination patterns.Bryan M. HooksAndrew E. PapaleRonald F. PaletzkiMuhammad W. FerozeBrian S. EastwoodJonathan J. CoueyJohan WinnubstJayaram ChandrashekarCharles R. GerfenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018) |
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Science Q Bryan M. Hooks Andrew E. Papale Ronald F. Paletzki Muhammad W. Feroze Brian S. Eastwood Jonathan J. Couey Johan Winnubst Jayaram Chandrashekar Charles R. Gerfen Topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area |
description |
How corticostriatal connections of different pyramidal cell types are organized, particularly in convergent circuits, has not been evaluated in detail. Here, cell type-specific Cre-driver mice reveal that pyramidal tract-type corticostriatal projections, though broadly similar to intratelencephalic-type projections from the same cortical region, are generally more restricted and variable in their topographic termination patterns. |
format |
article |
author |
Bryan M. Hooks Andrew E. Papale Ronald F. Paletzki Muhammad W. Feroze Brian S. Eastwood Jonathan J. Couey Johan Winnubst Jayaram Chandrashekar Charles R. Gerfen |
author_facet |
Bryan M. Hooks Andrew E. Papale Ronald F. Paletzki Muhammad W. Feroze Brian S. Eastwood Jonathan J. Couey Johan Winnubst Jayaram Chandrashekar Charles R. Gerfen |
author_sort |
Bryan M. Hooks |
title |
Topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area |
title_short |
Topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area |
title_full |
Topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area |
title_fullStr |
Topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area |
title_full_unstemmed |
Topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area |
title_sort |
topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/84c613a3ab84486487983e800ed1d0b3 |
work_keys_str_mv |
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