Topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area

How corticostriatal connections of different pyramidal cell types are organized, particularly in convergent circuits, has not been evaluated in detail. Here, cell type-specific Cre-driver mice reveal that pyramidal tract-type corticostriatal projections, though broadly similar to intratelencephalic-...

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Autores principales: Bryan M. Hooks, Andrew E. Papale, Ronald F. Paletzki, Muhammad W. Feroze, Brian S. Eastwood, Jonathan J. Couey, Johan Winnubst, Jayaram Chandrashekar, Charles R. Gerfen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/84c613a3ab84486487983e800ed1d0b3
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spelling oai:doaj.org-article:84c613a3ab84486487983e800ed1d0b32021-12-02T14:40:32ZTopographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area10.1038/s41467-018-05780-72041-1723https://doaj.org/article/84c613a3ab84486487983e800ed1d0b32018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05780-7https://doaj.org/toc/2041-1723How corticostriatal connections of different pyramidal cell types are organized, particularly in convergent circuits, has not been evaluated in detail. Here, cell type-specific Cre-driver mice reveal that pyramidal tract-type corticostriatal projections, though broadly similar to intratelencephalic-type projections from the same cortical region, are generally more restricted and variable in their topographic termination patterns.Bryan M. HooksAndrew E. PapaleRonald F. PaletzkiMuhammad W. FerozeBrian S. EastwoodJonathan J. CoueyJohan WinnubstJayaram ChandrashekarCharles R. GerfenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Bryan M. Hooks
Andrew E. Papale
Ronald F. Paletzki
Muhammad W. Feroze
Brian S. Eastwood
Jonathan J. Couey
Johan Winnubst
Jayaram Chandrashekar
Charles R. Gerfen
Topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area
description How corticostriatal connections of different pyramidal cell types are organized, particularly in convergent circuits, has not been evaluated in detail. Here, cell type-specific Cre-driver mice reveal that pyramidal tract-type corticostriatal projections, though broadly similar to intratelencephalic-type projections from the same cortical region, are generally more restricted and variable in their topographic termination patterns.
format article
author Bryan M. Hooks
Andrew E. Papale
Ronald F. Paletzki
Muhammad W. Feroze
Brian S. Eastwood
Jonathan J. Couey
Johan Winnubst
Jayaram Chandrashekar
Charles R. Gerfen
author_facet Bryan M. Hooks
Andrew E. Papale
Ronald F. Paletzki
Muhammad W. Feroze
Brian S. Eastwood
Jonathan J. Couey
Johan Winnubst
Jayaram Chandrashekar
Charles R. Gerfen
author_sort Bryan M. Hooks
title Topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area
title_short Topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area
title_full Topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area
title_fullStr Topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area
title_full_unstemmed Topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area
title_sort topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/84c613a3ab84486487983e800ed1d0b3
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