Disulfide HMGB1 acts via TLR2/4 receptors to reduce the numbers of oligodendrocyte progenitor cells after traumatic injury in vitro
Abstract Traumatic brain injury (TBI) is associated with poor clinical outcomes; autopsy studies of TBI victims demonstrate significant oligodendrocyte progenitor cell (OPC) death post TBI; an observation, which may explain the lack of meaningful repair of injured axons. Whilst high-mobility group b...
Enregistré dans:
Auteurs principaux: | R. Ved, F. Sharouf, B. Harari, M. Muzaffar, S. Manivannan, C. Ormonde, W. P. Gray, M. Zaben |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/84c6f53091dd46c88e22c6d49e403648 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
HMGB1/TLR4 Signaling Affects Regulatory T Cells in Acute Lung Injury
par: Zhou M, et autres
Publié: (2021) -
HMGB1 mediates endogenous TLR2 activation and brain tumor regression.
par: James F Curtin, et autres
Publié: (2009) -
Maslinic Acid Attenuates Ischemia/Reperfusion Injury-Induced Myocardial Inflammation and Apoptosis by Regulating HMGB1-TLR4 Axis
par: Qi Li, et autres
Publié: (2021) -
Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination
par: Darpan Saraswat, et autres
Publié: (2021) -
Prunella vulgaris L. Attenuates Experimental Autoimmune Thyroiditis by Inhibiting HMGB1/TLR9 Signaling
par: Guo Q, et autres
Publié: (2021)