TNFα-induced cardioprotection is independent of the activation of the prosurvival kinase Erk

Introduction: Tumour Necrosis Factor alpha (TNFα) contributes to cardiac dysfunction following ischaemia-reperfusion. Nonetheless, brief exposure to exogenous low doses of TNFα can mimic ischaemic preconditioning and thus be cardio-protective. The extracellular signal-regulated kinase (Erk) has been...

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Autores principales: Sarin Somers, Aurelien Engerer, Sandrine Lecour
Formato: article
Lenguaje:EN
Publicado: South African Heart Association 2017
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Acceso en línea:https://doaj.org/article/84d0d950263a4a23b28975884a299afd
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