Peripheral Blood Monocyte to Lymphocyte Ratio for Prediction of Tuberculous Pleuritis

Objective: To examine the peripheral monocyte to lymphocyte ratio (ML ratio) of patients with tuberculous (TB) pleuritis and the ML ratio changes after treatment. Methods: Clinical and laboratory information were collected from patients with lymphocytic exudative pleural effusion admitted to Chiang...

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Autores principales:	Pasa Sukson, Chalerm Liwsrisakun, Juthamas Inchai, Konlawij Trongtrakul, Pattraporn Tajarernmuang
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Monocytes Lymphocytes Tuberculosis Pleural effusion Pleural tuberculosis Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/84d7e14ed0084f4783606bcd2b07f1c7
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spelling	oai:doaj.org-article:84d7e14ed0084f4783606bcd2b07f1c72021-11-30T04:14:17ZPeripheral Blood Monocyte to Lymphocyte Ratio for Prediction of Tuberculous Pleuritis1201-971210.1016/j.ijid.2021.09.033https://doaj.org/article/84d7e14ed0084f4783606bcd2b07f1c72021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1201971221007384https://doaj.org/toc/1201-9712Objective: To examine the peripheral monocyte to lymphocyte ratio (ML ratio) of patients with tuberculous (TB) pleuritis and the ML ratio changes after treatment. Methods: Clinical and laboratory information were collected from patients with lymphocytic exudative pleural effusion admitted to Chiang Mai University Hospital from 2013 to 2019. This study compared the ML ratios between tuberculous pleuritis and other diagnoses in patients who were followed after treatment. Results: A total of 152 patients were included: 57 with tuberculous pleuritis and 95 with other lymphocytic exudates. The majority of non-tuberculous effusion was malignant pleural effusion. The mean ML ratio of each group was 0.72±0.29 and 0.34±0.13 (p<0.001). The Area Under the Receiver Operative Characteristic Curve of the ML ratio for diagnosing tuberculous pleuritis was 0.91. The best cut-off point of the ML ratio for diagnosing tuberculous pleuritis was >0.45, where the sensitivity and specificity were 82.5% and 86.3%, respectively. The ML ratio gradually reduced after the anti-TB treatment. ML ratios at 0, 2, and 6 months after the treatment were 0.72±0.29, 0.40±0.37, and 0.30±0.27, respectively (p<0.001). Conclusion: The peripheral blood ML ratio is an easy and useful tool for diagnosing and predicting the treatment response in patients with tuberculous pleuritis.Pasa SuksonChalerm LiwsrisakunJuthamas InchaiKonlawij TrongtrakulPattraporn TajarernmuangElsevierarticleMonocytesLymphocytesTuberculosisPleural effusionPleural tuberculosisInfectious and parasitic diseasesRC109-216ENInternational Journal of Infectious Diseases, Vol 112, Iss , Pp 212-216 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Monocytes Lymphocytes Tuberculosis Pleural effusion Pleural tuberculosis Infectious and parasitic diseases RC109-216
spellingShingle	Monocytes Lymphocytes Tuberculosis Pleural effusion Pleural tuberculosis Infectious and parasitic diseases RC109-216 Pasa Sukson Chalerm Liwsrisakun Juthamas Inchai Konlawij Trongtrakul Pattraporn Tajarernmuang Peripheral Blood Monocyte to Lymphocyte Ratio for Prediction of Tuberculous Pleuritis
description	Objective: To examine the peripheral monocyte to lymphocyte ratio (ML ratio) of patients with tuberculous (TB) pleuritis and the ML ratio changes after treatment. Methods: Clinical and laboratory information were collected from patients with lymphocytic exudative pleural effusion admitted to Chiang Mai University Hospital from 2013 to 2019. This study compared the ML ratios between tuberculous pleuritis and other diagnoses in patients who were followed after treatment. Results: A total of 152 patients were included: 57 with tuberculous pleuritis and 95 with other lymphocytic exudates. The majority of non-tuberculous effusion was malignant pleural effusion. The mean ML ratio of each group was 0.72±0.29 and 0.34±0.13 (p<0.001). The Area Under the Receiver Operative Characteristic Curve of the ML ratio for diagnosing tuberculous pleuritis was 0.91. The best cut-off point of the ML ratio for diagnosing tuberculous pleuritis was >0.45, where the sensitivity and specificity were 82.5% and 86.3%, respectively. The ML ratio gradually reduced after the anti-TB treatment. ML ratios at 0, 2, and 6 months after the treatment were 0.72±0.29, 0.40±0.37, and 0.30±0.27, respectively (p<0.001). Conclusion: The peripheral blood ML ratio is an easy and useful tool for diagnosing and predicting the treatment response in patients with tuberculous pleuritis.
format	article
author	Pasa Sukson Chalerm Liwsrisakun Juthamas Inchai Konlawij Trongtrakul Pattraporn Tajarernmuang
author_facet	Pasa Sukson Chalerm Liwsrisakun Juthamas Inchai Konlawij Trongtrakul Pattraporn Tajarernmuang
author_sort	Pasa Sukson
title	Peripheral Blood Monocyte to Lymphocyte Ratio for Prediction of Tuberculous Pleuritis
title_short	Peripheral Blood Monocyte to Lymphocyte Ratio for Prediction of Tuberculous Pleuritis
title_full	Peripheral Blood Monocyte to Lymphocyte Ratio for Prediction of Tuberculous Pleuritis
title_fullStr	Peripheral Blood Monocyte to Lymphocyte Ratio for Prediction of Tuberculous Pleuritis
title_full_unstemmed	Peripheral Blood Monocyte to Lymphocyte Ratio for Prediction of Tuberculous Pleuritis
title_sort	peripheral blood monocyte to lymphocyte ratio for prediction of tuberculous pleuritis
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/84d7e14ed0084f4783606bcd2b07f1c7
work_keys_str_mv	AT pasasukson peripheralbloodmonocytetolymphocyteratioforpredictionoftuberculouspleuritis AT chalermliwsrisakun peripheralbloodmonocytetolymphocyteratioforpredictionoftuberculouspleuritis AT juthamasinchai peripheralbloodmonocytetolymphocyteratioforpredictionoftuberculouspleuritis AT konlawijtrongtrakul peripheralbloodmonocytetolymphocyteratioforpredictionoftuberculouspleuritis AT pattraporntajarernmuang peripheralbloodmonocytetolymphocyteratioforpredictionoftuberculouspleuritis
_version_	1718406815839944704

Peripheral Blood Monocyte to Lymphocyte Ratio for Prediction of Tuberculous Pleuritis

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