Comparison of Lidocaine-Nitroglycerine with Lidocaine for Intravenous Regional Anesthesia

BACKGROUND AND OBJECTIVE: Intravenous regional anesthesia (IVRA) is a simple and reliable method for upper extremity injuries. Different additives have been combined with local anesthetics to improve block quality, decrease tourniquet pain and postoperative analgesia in IVRA. This study was performe...

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Autores principales: Nadia Banihashem, Bahman Hasan Nasab, Ebrahim Alijanpour, Hakimeh Alereza, Abolhasan Taheri, V Hosseini, Ali Bijani
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Publicado: Babol University of Medical Sciences 2012
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Acceso en línea:https://doaj.org/article/84e4e381fdd94776a22f9deb961c1236
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spelling oai:doaj.org-article:84e4e381fdd94776a22f9deb961c12362021-11-10T08:52:02ZComparison of Lidocaine-Nitroglycerine with Lidocaine for Intravenous Regional Anesthesia1561-41072251-7170https://doaj.org/article/84e4e381fdd94776a22f9deb961c12362012-01-01T00:00:00Zhttp://jbums.org/article-1-3977-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Intravenous regional anesthesia (IVRA) is a simple and reliable method for upper extremity injuries. Different additives have been combined with local anesthetics to improve block quality, decrease tourniquet pain and postoperative analgesia in IVRA. This study was performed to evaluate the effect of nitroglycerine on tourniquet pain and intraoperative analgesia when added to lidocaine for IV regional anesthesia. METHODS: In a clinical trial, 50 patients with upper extremity injury were scheduled for IVRA, randomly allocated into two groups. They were unified by age and gender. Under identical condition, control group received a total dose of 200 mg lidocaine diluted with saline (40 cc) and study group received 200 mg lidocaine plus 200 µg nitroglycerine diluted with saline (40 cc). Anesthesia quality, tourniquet pain and opioid requirement were measured during surgery. After the tourniquet deflation, time to first analgesic requirement was noted. FINDINGS: Intraoperative pain scores were not different between two groups and fentanyl requirement was similar. The onset of tourniquet pain was similar in case (21.96±3.87 min) and control group (21.12±3.33 min) (p=0.41). Analgesia time and time of initial analgesic requirement after tourniquet deflation was 54.4±9.95 min in control group and 60.40±10.17 min in case group (p=0.625). CONCLUSION: Addition of nitroglycerine to lidocaine was not improved the quality of IVRA, postoperative analgesia and opioid requirements in patients undergoing hand surgery.Nadia BanihashemBahman Hasan NasabEbrahim AlijanpourHakimeh AlerezaAbolhasan TaheriV HosseiniAli BijaniBabol University of Medical Sciencesarticlenitroglycerinelidocaineintravenous regional anesthesiaanalgesiaMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 14, Iss 1, Pp 7-12 (2012)
institution DOAJ
collection DOAJ
language EN
FA
topic nitroglycerine
lidocaine
intravenous regional anesthesia
analgesia
Medicine
R
Medicine (General)
R5-920
spellingShingle nitroglycerine
lidocaine
intravenous regional anesthesia
analgesia
Medicine
R
Medicine (General)
R5-920
Nadia Banihashem
Bahman Hasan Nasab
Ebrahim Alijanpour
Hakimeh Alereza
Abolhasan Taheri
V Hosseini
Ali Bijani
Comparison of Lidocaine-Nitroglycerine with Lidocaine for Intravenous Regional Anesthesia
description BACKGROUND AND OBJECTIVE: Intravenous regional anesthesia (IVRA) is a simple and reliable method for upper extremity injuries. Different additives have been combined with local anesthetics to improve block quality, decrease tourniquet pain and postoperative analgesia in IVRA. This study was performed to evaluate the effect of nitroglycerine on tourniquet pain and intraoperative analgesia when added to lidocaine for IV regional anesthesia. METHODS: In a clinical trial, 50 patients with upper extremity injury were scheduled for IVRA, randomly allocated into two groups. They were unified by age and gender. Under identical condition, control group received a total dose of 200 mg lidocaine diluted with saline (40 cc) and study group received 200 mg lidocaine plus 200 µg nitroglycerine diluted with saline (40 cc). Anesthesia quality, tourniquet pain and opioid requirement were measured during surgery. After the tourniquet deflation, time to first analgesic requirement was noted. FINDINGS: Intraoperative pain scores were not different between two groups and fentanyl requirement was similar. The onset of tourniquet pain was similar in case (21.96±3.87 min) and control group (21.12±3.33 min) (p=0.41). Analgesia time and time of initial analgesic requirement after tourniquet deflation was 54.4±9.95 min in control group and 60.40±10.17 min in case group (p=0.625). CONCLUSION: Addition of nitroglycerine to lidocaine was not improved the quality of IVRA, postoperative analgesia and opioid requirements in patients undergoing hand surgery.
format article
author Nadia Banihashem
Bahman Hasan Nasab
Ebrahim Alijanpour
Hakimeh Alereza
Abolhasan Taheri
V Hosseini
Ali Bijani
author_facet Nadia Banihashem
Bahman Hasan Nasab
Ebrahim Alijanpour
Hakimeh Alereza
Abolhasan Taheri
V Hosseini
Ali Bijani
author_sort Nadia Banihashem
title Comparison of Lidocaine-Nitroglycerine with Lidocaine for Intravenous Regional Anesthesia
title_short Comparison of Lidocaine-Nitroglycerine with Lidocaine for Intravenous Regional Anesthesia
title_full Comparison of Lidocaine-Nitroglycerine with Lidocaine for Intravenous Regional Anesthesia
title_fullStr Comparison of Lidocaine-Nitroglycerine with Lidocaine for Intravenous Regional Anesthesia
title_full_unstemmed Comparison of Lidocaine-Nitroglycerine with Lidocaine for Intravenous Regional Anesthesia
title_sort comparison of lidocaine-nitroglycerine with lidocaine for intravenous regional anesthesia
publisher Babol University of Medical Sciences
publishDate 2012
url https://doaj.org/article/84e4e381fdd94776a22f9deb961c1236
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