Principles of meiotic chromosome assembly revealed in S. cerevisiae

During meiotic prophase chromosomes organise into a series of chromatin loops, but the mechanisms of assembly remain unclear. Here the authors use Saccharomyces cerevisiae to elucidate how this elaborate three-dimensional chromosome organisation is linked to genomic sequence, and demonstrate an esse...

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Autores principales:	Stephanie A. Schalbetter, Geoffrey Fudenberg, Jonathan Baxter, Katherine S. Pollard, Matthew J. Neale
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/84ecfc1430184d14b70e93aefe94dc8c
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id	oai:doaj.org-article:84ecfc1430184d14b70e93aefe94dc8c
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spelling	oai:doaj.org-article:84ecfc1430184d14b70e93aefe94dc8c2021-12-02T14:38:40ZPrinciples of meiotic chromosome assembly revealed in S. cerevisiae10.1038/s41467-019-12629-02041-1723https://doaj.org/article/84ecfc1430184d14b70e93aefe94dc8c2019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12629-0https://doaj.org/toc/2041-1723During meiotic prophase chromosomes organise into a series of chromatin loops, but the mechanisms of assembly remain unclear. Here the authors use Saccharomyces cerevisiae to elucidate how this elaborate three-dimensional chromosome organisation is linked to genomic sequence, and demonstrate an essential role for cohesin during this process.Stephanie A. SchalbetterGeoffrey FudenbergJonathan BaxterKatherine S. PollardMatthew J. NealeNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Stephanie A. Schalbetter Geoffrey Fudenberg Jonathan Baxter Katherine S. Pollard Matthew J. Neale Principles of meiotic chromosome assembly revealed in S. cerevisiae
description	During meiotic prophase chromosomes organise into a series of chromatin loops, but the mechanisms of assembly remain unclear. Here the authors use Saccharomyces cerevisiae to elucidate how this elaborate three-dimensional chromosome organisation is linked to genomic sequence, and demonstrate an essential role for cohesin during this process.
format	article
author	Stephanie A. Schalbetter Geoffrey Fudenberg Jonathan Baxter Katherine S. Pollard Matthew J. Neale
author_facet	Stephanie A. Schalbetter Geoffrey Fudenberg Jonathan Baxter Katherine S. Pollard Matthew J. Neale
author_sort	Stephanie A. Schalbetter
title	Principles of meiotic chromosome assembly revealed in S. cerevisiae
title_short	Principles of meiotic chromosome assembly revealed in S. cerevisiae
title_full	Principles of meiotic chromosome assembly revealed in S. cerevisiae
title_fullStr	Principles of meiotic chromosome assembly revealed in S. cerevisiae
title_full_unstemmed	Principles of meiotic chromosome assembly revealed in S. cerevisiae
title_sort	principles of meiotic chromosome assembly revealed in s. cerevisiae
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/84ecfc1430184d14b70e93aefe94dc8c
work_keys_str_mv	AT stephanieaschalbetter principlesofmeioticchromosomeassemblyrevealedinscerevisiae AT geoffreyfudenberg principlesofmeioticchromosomeassemblyrevealedinscerevisiae AT jonathanbaxter principlesofmeioticchromosomeassemblyrevealedinscerevisiae AT katherinespollard principlesofmeioticchromosomeassemblyrevealedinscerevisiae AT matthewjneale principlesofmeioticchromosomeassemblyrevealedinscerevisiae
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Principles of meiotic chromosome assembly revealed in S. cerevisiae

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