Extremely low frequency magnetic field (50 Hz, 0.5 mT) reduces oxidative stress in the brain of gerbils submitted to global cerebral ischemia.

Magnetic field as ecological factor has influence on all living beings. The aim of this study was to determine if extremely low frequency magnetic field (ELF-MF, 50 Hz, 0.5 mT) affects oxidative stress in the brain of gerbils submitted to 10-min global cerebral ischemia. After occlusion of both caro...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Snežana Rauš Balind, Vesna Selaković, Lidija Radenović, Zlatko Prolić, Branka Janać
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/84ed09bd8cc24d0fa2b33ada13082b49
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:84ed09bd8cc24d0fa2b33ada13082b49
record_format	dspace
spelling	oai:doaj.org-article:84ed09bd8cc24d0fa2b33ada13082b492021-11-18T08:32:02ZExtremely low frequency magnetic field (50 Hz, 0.5 mT) reduces oxidative stress in the brain of gerbils submitted to global cerebral ischemia.1932-620310.1371/journal.pone.0088921https://doaj.org/article/84ed09bd8cc24d0fa2b33ada13082b492014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24586442/?tool=EBIhttps://doaj.org/toc/1932-6203Magnetic field as ecological factor has influence on all living beings. The aim of this study was to determine if extremely low frequency magnetic field (ELF-MF, 50 Hz, 0.5 mT) affects oxidative stress in the brain of gerbils submitted to 10-min global cerebral ischemia. After occlusion of both carotid arteries, 3-month-old gerbils were continuously exposed to ELF-MF for 7 days. Nitric oxide and superoxide anion production, superoxide dismutase activity and index of lipid peroxidation were examined in the forebrain cortex, striatum and hippocampus on the 7(th) (immediate effect of ELF-MF) and 14(th) day after reperfusion (delayed effect of ELF-MF). Ischemia per se increased oxidative stress in the brain on the 7(th) and 14(th) day after reperfusion. ELF-MF also increased oxidative stress, but to a greater extent than ischemia, only immediately after cessation of exposure. Ischemic gerbils exposed to ELF-MF had increased oxidative stress parameters on the 7(th) day after reperfusion, but to a lesser extent than ischemic or ELF-MF-exposed animals. On the 14(th) day after reperfusion, oxidative stress parameters in the brain of these gerbils were mostly at the control levels. Applied ELF-MF decreases oxidative stress induced by global cerebral ischemia and thereby reduces possible negative consequences which free radical species could have in the brain. The results presented here indicate a beneficial effect of ELF-MF (50 Hz, 0.5 mT) in the model of global cerebral ischemia.Snežana Rauš BalindVesna SelakovićLidija RadenovićZlatko ProlićBranka JanaćPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 2, p e88921 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Snežana Rauš Balind Vesna Selaković Lidija Radenović Zlatko Prolić Branka Janać Extremely low frequency magnetic field (50 Hz, 0.5 mT) reduces oxidative stress in the brain of gerbils submitted to global cerebral ischemia.
description	Magnetic field as ecological factor has influence on all living beings. The aim of this study was to determine if extremely low frequency magnetic field (ELF-MF, 50 Hz, 0.5 mT) affects oxidative stress in the brain of gerbils submitted to 10-min global cerebral ischemia. After occlusion of both carotid arteries, 3-month-old gerbils were continuously exposed to ELF-MF for 7 days. Nitric oxide and superoxide anion production, superoxide dismutase activity and index of lipid peroxidation were examined in the forebrain cortex, striatum and hippocampus on the 7(th) (immediate effect of ELF-MF) and 14(th) day after reperfusion (delayed effect of ELF-MF). Ischemia per se increased oxidative stress in the brain on the 7(th) and 14(th) day after reperfusion. ELF-MF also increased oxidative stress, but to a greater extent than ischemia, only immediately after cessation of exposure. Ischemic gerbils exposed to ELF-MF had increased oxidative stress parameters on the 7(th) day after reperfusion, but to a lesser extent than ischemic or ELF-MF-exposed animals. On the 14(th) day after reperfusion, oxidative stress parameters in the brain of these gerbils were mostly at the control levels. Applied ELF-MF decreases oxidative stress induced by global cerebral ischemia and thereby reduces possible negative consequences which free radical species could have in the brain. The results presented here indicate a beneficial effect of ELF-MF (50 Hz, 0.5 mT) in the model of global cerebral ischemia.
format	article
author	Snežana Rauš Balind Vesna Selaković Lidija Radenović Zlatko Prolić Branka Janać
author_facet	Snežana Rauš Balind Vesna Selaković Lidija Radenović Zlatko Prolić Branka Janać
author_sort	Snežana Rauš Balind
title	Extremely low frequency magnetic field (50 Hz, 0.5 mT) reduces oxidative stress in the brain of gerbils submitted to global cerebral ischemia.
title_short	Extremely low frequency magnetic field (50 Hz, 0.5 mT) reduces oxidative stress in the brain of gerbils submitted to global cerebral ischemia.
title_full	Extremely low frequency magnetic field (50 Hz, 0.5 mT) reduces oxidative stress in the brain of gerbils submitted to global cerebral ischemia.
title_fullStr	Extremely low frequency magnetic field (50 Hz, 0.5 mT) reduces oxidative stress in the brain of gerbils submitted to global cerebral ischemia.
title_full_unstemmed	Extremely low frequency magnetic field (50 Hz, 0.5 mT) reduces oxidative stress in the brain of gerbils submitted to global cerebral ischemia.
title_sort	extremely low frequency magnetic field (50 hz, 0.5 mt) reduces oxidative stress in the brain of gerbils submitted to global cerebral ischemia.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/84ed09bd8cc24d0fa2b33ada13082b49
work_keys_str_mv	AT snezanarausbalind extremelylowfrequencymagneticfield50hz05mtreducesoxidativestressinthebrainofgerbilssubmittedtoglobalcerebralischemia AT vesnaselakovic extremelylowfrequencymagneticfield50hz05mtreducesoxidativestressinthebrainofgerbilssubmittedtoglobalcerebralischemia AT lidijaradenovic extremelylowfrequencymagneticfield50hz05mtreducesoxidativestressinthebrainofgerbilssubmittedtoglobalcerebralischemia AT zlatkoprolic extremelylowfrequencymagneticfield50hz05mtreducesoxidativestressinthebrainofgerbilssubmittedtoglobalcerebralischemia AT brankajanac extremelylowfrequencymagneticfield50hz05mtreducesoxidativestressinthebrainofgerbilssubmittedtoglobalcerebralischemia
_version_	1718421693626580992

Extremely low frequency magnetic field (50 Hz, 0.5 mT) reduces oxidative stress in the brain of gerbils submitted to global cerebral ischemia.

Ejemplares similares