Re-designing Interleukin-12 to enhance its safety and potential as an anti-tumor immunotherapeutic agent
Interleukin-12 (IL-12) is a potent immunotherapeutic agent.
Saved in:
Main Authors: | , , , , , , , , , , , , , , , , |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
|
Subjects: | |
Online Access: | https://doaj.org/article/84f37118338744888cbe6343b27f3c3f |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
oai:doaj.org-article:84f37118338744888cbe6343b27f3c3f |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:84f37118338744888cbe6343b27f3c3f2021-12-02T14:40:21ZRe-designing Interleukin-12 to enhance its safety and potential as an anti-tumor immunotherapeutic agent10.1038/s41467-017-01385-82041-1723https://doaj.org/article/84f37118338744888cbe6343b27f3c3f2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01385-8https://doaj.org/toc/2041-1723Interleukin-12 (IL-12) is a potent immunotherapeutic agent.Pengju WangXiaozhu LiJiwei WangDongling GaoYuenan LiHaoze LiYongchao ChuZhongxian ZhangHongtao LiuGuozhong JiangZhenguo ChengShengdian WangJianzeng DongBaisui FengLouisa S. ChardNicholas R. LemoineYaohe WangNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Pengju Wang Xiaozhu Li Jiwei Wang Dongling Gao Yuenan Li Haoze Li Yongchao Chu Zhongxian Zhang Hongtao Liu Guozhong Jiang Zhenguo Cheng Shengdian Wang Jianzeng Dong Baisui Feng Louisa S. Chard Nicholas R. Lemoine Yaohe Wang Re-designing Interleukin-12 to enhance its safety and potential as an anti-tumor immunotherapeutic agent |
description |
Interleukin-12 (IL-12) is a potent immunotherapeutic agent. |
format |
article |
author |
Pengju Wang Xiaozhu Li Jiwei Wang Dongling Gao Yuenan Li Haoze Li Yongchao Chu Zhongxian Zhang Hongtao Liu Guozhong Jiang Zhenguo Cheng Shengdian Wang Jianzeng Dong Baisui Feng Louisa S. Chard Nicholas R. Lemoine Yaohe Wang |
author_facet |
Pengju Wang Xiaozhu Li Jiwei Wang Dongling Gao Yuenan Li Haoze Li Yongchao Chu Zhongxian Zhang Hongtao Liu Guozhong Jiang Zhenguo Cheng Shengdian Wang Jianzeng Dong Baisui Feng Louisa S. Chard Nicholas R. Lemoine Yaohe Wang |
author_sort |
Pengju Wang |
title |
Re-designing Interleukin-12 to enhance its safety and potential as an anti-tumor immunotherapeutic agent |
title_short |
Re-designing Interleukin-12 to enhance its safety and potential as an anti-tumor immunotherapeutic agent |
title_full |
Re-designing Interleukin-12 to enhance its safety and potential as an anti-tumor immunotherapeutic agent |
title_fullStr |
Re-designing Interleukin-12 to enhance its safety and potential as an anti-tumor immunotherapeutic agent |
title_full_unstemmed |
Re-designing Interleukin-12 to enhance its safety and potential as an anti-tumor immunotherapeutic agent |
title_sort |
re-designing interleukin-12 to enhance its safety and potential as an anti-tumor immunotherapeutic agent |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/84f37118338744888cbe6343b27f3c3f |
work_keys_str_mv |
AT pengjuwang redesigninginterleukin12toenhanceitssafetyandpotentialasanantitumorimmunotherapeuticagent AT xiaozhuli redesigninginterleukin12toenhanceitssafetyandpotentialasanantitumorimmunotherapeuticagent AT jiweiwang redesigninginterleukin12toenhanceitssafetyandpotentialasanantitumorimmunotherapeuticagent AT donglinggao redesigninginterleukin12toenhanceitssafetyandpotentialasanantitumorimmunotherapeuticagent AT yuenanli redesigninginterleukin12toenhanceitssafetyandpotentialasanantitumorimmunotherapeuticagent AT haozeli redesigninginterleukin12toenhanceitssafetyandpotentialasanantitumorimmunotherapeuticagent AT yongchaochu redesigninginterleukin12toenhanceitssafetyandpotentialasanantitumorimmunotherapeuticagent AT zhongxianzhang redesigninginterleukin12toenhanceitssafetyandpotentialasanantitumorimmunotherapeuticagent AT hongtaoliu redesigninginterleukin12toenhanceitssafetyandpotentialasanantitumorimmunotherapeuticagent AT guozhongjiang redesigninginterleukin12toenhanceitssafetyandpotentialasanantitumorimmunotherapeuticagent AT zhenguocheng redesigninginterleukin12toenhanceitssafetyandpotentialasanantitumorimmunotherapeuticagent AT shengdianwang redesigninginterleukin12toenhanceitssafetyandpotentialasanantitumorimmunotherapeuticagent AT jianzengdong redesigninginterleukin12toenhanceitssafetyandpotentialasanantitumorimmunotherapeuticagent AT baisuifeng redesigninginterleukin12toenhanceitssafetyandpotentialasanantitumorimmunotherapeuticagent AT louisaschard redesigninginterleukin12toenhanceitssafetyandpotentialasanantitumorimmunotherapeuticagent AT nicholasrlemoine redesigninginterleukin12toenhanceitssafetyandpotentialasanantitumorimmunotherapeuticagent AT yaohewang redesigninginterleukin12toenhanceitssafetyandpotentialasanantitumorimmunotherapeuticagent |
_version_ |
1718390307219832832 |