The Crohn’s disease-related bacterial strain LF82 assembles biofilm-like communities to protect itself from phagolysosomal attack

Prudent et al. show that intracellular bacteria related to the Crohn’s disease, LF82, produce an extra-bacterial matrix that acts as a biofilm and controls the formation of LF82 intracellular bacterial communities. This study provides insights into the strategies that adherent invasive E. coli use t...

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Autores principales: Victoria Prudent, Gaëlle Demarre, Emilie Vazeille, Maxime Wery, Nicole Quenech’Du, Antinéa Ravet, Julie Dauverd - Girault, Erwin van Dijk, Marie-Agnès Bringer, Marc Descrimes, Nicolas Barnich, Sylvie Rimsky, Antonin Morillon, Olivier Espéli
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/84f597f09eaf4c2a98fbf4d886389a93
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Sumario:Prudent et al. show that intracellular bacteria related to the Crohn’s disease, LF82, produce an extra-bacterial matrix that acts as a biofilm and controls the formation of LF82 intracellular bacterial communities. This study provides insights into the strategies that adherent invasive E. coli use to establish their replicative niche within macrophages.