Hyocholic acid species as novel biomarkers for metabolic disorders

The early identification of metabolic disorders could improve or prevent overt disease. Here the authors show that the circulating concentration of hyocholic acid (HCA) species is decreased in the context of obesity and diabetes and increased after gastric bypass surgery in humans, and further that...

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Autores principales:	Xiaojiao Zheng, Tianlu Chen, Aihua Zhao, Zhangchi Ning, Junliang Kuang, Shouli Wang, Yijun You, Yuqian Bao, Xiaojing Ma, Haoyong Yu, Jian Zhou, Miao Jiang, Mengci Li, Jieyi Wang, Xiaohui Ma, Shuiping Zhou, Yitao Li, Kun Ge, Cynthia Rajani, Guoxiang Xie, Cheng Hu, Yike Guo, Aiping Lu, Weiping Jia, Wei Jia
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/84f9292cb3a24136b8f421281afee4ad
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spelling	oai:doaj.org-article:84f9292cb3a24136b8f421281afee4ad2021-12-02T13:14:59ZHyocholic acid species as novel biomarkers for metabolic disorders10.1038/s41467-021-21744-w2041-1723https://doaj.org/article/84f9292cb3a24136b8f421281afee4ad2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21744-whttps://doaj.org/toc/2041-1723The early identification of metabolic disorders could improve or prevent overt disease. Here the authors show that the circulating concentration of hyocholic acid (HCA) species is decreased in the context of obesity and diabetes and increased after gastric bypass surgery in humans, and further that serum HCA species are predictive of metabolic outcomes in healthy individuals.Xiaojiao ZhengTianlu ChenAihua ZhaoZhangchi NingJunliang KuangShouli WangYijun YouYuqian BaoXiaojing MaHaoyong YuJian ZhouMiao JiangMengci LiJieyi WangXiaohui MaShuiping ZhouYitao LiKun GeCynthia RajaniGuoxiang XieCheng HuYike GuoAiping LuWeiping JiaWei JiaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xiaojiao Zheng Tianlu Chen Aihua Zhao Zhangchi Ning Junliang Kuang Shouli Wang Yijun You Yuqian Bao Xiaojing Ma Haoyong Yu Jian Zhou Miao Jiang Mengci Li Jieyi Wang Xiaohui Ma Shuiping Zhou Yitao Li Kun Ge Cynthia Rajani Guoxiang Xie Cheng Hu Yike Guo Aiping Lu Weiping Jia Wei Jia Hyocholic acid species as novel biomarkers for metabolic disorders
description	The early identification of metabolic disorders could improve or prevent overt disease. Here the authors show that the circulating concentration of hyocholic acid (HCA) species is decreased in the context of obesity and diabetes and increased after gastric bypass surgery in humans, and further that serum HCA species are predictive of metabolic outcomes in healthy individuals.
format	article
author	Xiaojiao Zheng Tianlu Chen Aihua Zhao Zhangchi Ning Junliang Kuang Shouli Wang Yijun You Yuqian Bao Xiaojing Ma Haoyong Yu Jian Zhou Miao Jiang Mengci Li Jieyi Wang Xiaohui Ma Shuiping Zhou Yitao Li Kun Ge Cynthia Rajani Guoxiang Xie Cheng Hu Yike Guo Aiping Lu Weiping Jia Wei Jia
author_facet	Xiaojiao Zheng Tianlu Chen Aihua Zhao Zhangchi Ning Junliang Kuang Shouli Wang Yijun You Yuqian Bao Xiaojing Ma Haoyong Yu Jian Zhou Miao Jiang Mengci Li Jieyi Wang Xiaohui Ma Shuiping Zhou Yitao Li Kun Ge Cynthia Rajani Guoxiang Xie Cheng Hu Yike Guo Aiping Lu Weiping Jia Wei Jia
author_sort	Xiaojiao Zheng
title	Hyocholic acid species as novel biomarkers for metabolic disorders
title_short	Hyocholic acid species as novel biomarkers for metabolic disorders
title_full	Hyocholic acid species as novel biomarkers for metabolic disorders
title_fullStr	Hyocholic acid species as novel biomarkers for metabolic disorders
title_full_unstemmed	Hyocholic acid species as novel biomarkers for metabolic disorders
title_sort	hyocholic acid species as novel biomarkers for metabolic disorders
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/84f9292cb3a24136b8f421281afee4ad
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Hyocholic acid species as novel biomarkers for metabolic disorders

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