A Tool for Rapid Assessment of Functional Outcomes in Patients with Head and Neck Cancer

Head and neck cancer (HNC) and its treatment can lead to various functional impairments. We developed and validated an instrument for rapid physician-rated assessment of basic functional outcomes in HNC patients. HNC-relevant functional domains were identified through a literature review and assigne...

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Autores principales:	Daniel Dejaco, David Riedl, Sebastian Gasser, Volker Hans Schartinger, Veronika Innerhofer, Timo Gottfried, Teresa Bernadette Steinbichler, Felix Riechelmann, Roland Moschen, Oliver Galvan, Robert Stigler, Robert Gassner, Gerhard Rumpold, Anna Lettenbichler-Haug, Herbert Riechelmann
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	head and neck neoplasms health status functional outcomes surveys and questionnaires questionnaire design Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/85029d2b0f9c414d93743714aa0588e4
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spelling	oai:doaj.org-article:85029d2b0f9c414d93743714aa0588e42021-11-11T15:33:56ZA Tool for Rapid Assessment of Functional Outcomes in Patients with Head and Neck Cancer10.3390/cancers132155292072-6694https://doaj.org/article/85029d2b0f9c414d93743714aa0588e42021-11-01T00:00:00Zhttps://www.mdpi.com/2072-6694/13/21/5529https://doaj.org/toc/2072-6694Head and neck cancer (HNC) and its treatment can lead to various functional impairments. We developed and validated an instrument for rapid physician-rated assessment of basic functional outcomes in HNC patients. HNC-relevant functional domains were identified through a literature review and assigned to verbal ratings based on observable criteria. The instrument draft was subjected to systematic expert review to assess its face and content validity. Finally, the empirical validity, reliability, and responsiveness of the expert-adapted Functional Integrity in Head and Neck Cancer (HNC-FIT) scales were assessed in healthy controls and in HNC patients. A matrix of the 6 functional domains of oral food intake, respiration, speech, pain, mood, and neck and shoulder mobility was created, each with 5 verbal rating levels. Face and content validity levels of the HNC-FIT scales were judged to be adequate by 17 experts. In 37 control subjects, 24 patients with HNC before treatment, and in 60 HNC patients after treatment, the HNC-FIT ratings in the 3 groups behaved as expected and functional domains correlated closely with the outcome of corresponding scales of the EORTC-HN35-QoL questionnaire, indicating good construct and criterion validity. Interrater reliability (rICC) was ≥0.9 for all functional domains and retest reliability (rICC) was ≥0.93 for all domains except mood (rICC = 0.71). The treatment effect size (eta-square) as a measure of responsiveness was ≥0.15 (<i>p</i> < 0.01) for fall domains except for breathing and neck and shoulder mobility. The median HNC-FIT scale completion time was 1 min 17 s. The HNC-FIT scale is a rapid tool for physician-rated assessment of functional outcomes in HNC patients with good validity, reliability, and responsiveness.Daniel DejacoDavid RiedlSebastian GasserVolker Hans SchartingerVeronika InnerhoferTimo GottfriedTeresa Bernadette SteinbichlerFelix RiechelmannRoland MoschenOliver GalvanRobert StiglerRobert GassnerGerhard RumpoldAnna Lettenbichler-HaugHerbert RiechelmannMDPI AGarticlehead and neck neoplasmshealth statusfunctional outcomessurveys and questionnairesquestionnaire designNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENCancers, Vol 13, Iss 5529, p 5529 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	head and neck neoplasms health status functional outcomes surveys and questionnaires questionnaire design Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	head and neck neoplasms health status functional outcomes surveys and questionnaires questionnaire design Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Daniel Dejaco David Riedl Sebastian Gasser Volker Hans Schartinger Veronika Innerhofer Timo Gottfried Teresa Bernadette Steinbichler Felix Riechelmann Roland Moschen Oliver Galvan Robert Stigler Robert Gassner Gerhard Rumpold Anna Lettenbichler-Haug Herbert Riechelmann A Tool for Rapid Assessment of Functional Outcomes in Patients with Head and Neck Cancer
description	Head and neck cancer (HNC) and its treatment can lead to various functional impairments. We developed and validated an instrument for rapid physician-rated assessment of basic functional outcomes in HNC patients. HNC-relevant functional domains were identified through a literature review and assigned to verbal ratings based on observable criteria. The instrument draft was subjected to systematic expert review to assess its face and content validity. Finally, the empirical validity, reliability, and responsiveness of the expert-adapted Functional Integrity in Head and Neck Cancer (HNC-FIT) scales were assessed in healthy controls and in HNC patients. A matrix of the 6 functional domains of oral food intake, respiration, speech, pain, mood, and neck and shoulder mobility was created, each with 5 verbal rating levels. Face and content validity levels of the HNC-FIT scales were judged to be adequate by 17 experts. In 37 control subjects, 24 patients with HNC before treatment, and in 60 HNC patients after treatment, the HNC-FIT ratings in the 3 groups behaved as expected and functional domains correlated closely with the outcome of corresponding scales of the EORTC-HN35-QoL questionnaire, indicating good construct and criterion validity. Interrater reliability (rICC) was ≥0.9 for all functional domains and retest reliability (rICC) was ≥0.93 for all domains except mood (rICC = 0.71). The treatment effect size (eta-square) as a measure of responsiveness was ≥0.15 (<i>p</i> < 0.01) for fall domains except for breathing and neck and shoulder mobility. The median HNC-FIT scale completion time was 1 min 17 s. The HNC-FIT scale is a rapid tool for physician-rated assessment of functional outcomes in HNC patients with good validity, reliability, and responsiveness.
format	article
author	Daniel Dejaco David Riedl Sebastian Gasser Volker Hans Schartinger Veronika Innerhofer Timo Gottfried Teresa Bernadette Steinbichler Felix Riechelmann Roland Moschen Oliver Galvan Robert Stigler Robert Gassner Gerhard Rumpold Anna Lettenbichler-Haug Herbert Riechelmann
author_facet	Daniel Dejaco David Riedl Sebastian Gasser Volker Hans Schartinger Veronika Innerhofer Timo Gottfried Teresa Bernadette Steinbichler Felix Riechelmann Roland Moschen Oliver Galvan Robert Stigler Robert Gassner Gerhard Rumpold Anna Lettenbichler-Haug Herbert Riechelmann
author_sort	Daniel Dejaco
title	A Tool for Rapid Assessment of Functional Outcomes in Patients with Head and Neck Cancer
title_short	A Tool for Rapid Assessment of Functional Outcomes in Patients with Head and Neck Cancer
title_full	A Tool for Rapid Assessment of Functional Outcomes in Patients with Head and Neck Cancer
title_fullStr	A Tool for Rapid Assessment of Functional Outcomes in Patients with Head and Neck Cancer
title_full_unstemmed	A Tool for Rapid Assessment of Functional Outcomes in Patients with Head and Neck Cancer
title_sort	tool for rapid assessment of functional outcomes in patients with head and neck cancer
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/85029d2b0f9c414d93743714aa0588e4
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A Tool for Rapid Assessment of Functional Outcomes in Patients with Head and Neck Cancer

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