KRAS Activation and over-expression of SIRT1/BCL6 Contributes to the Pathogenesis of Endometriosis and Progesterone Resistance

KRAS Activation and over-expression of SIRT1/BCL6 Contributes to the Pathogenesis of Endometriosis and Progesterone Resistance

Abstract Endometriosis is an inflammatory condition that is associated with progesterone resistance and cell proliferation, resulting in pain, infertility and pregnancy loss. We previously demonstrated phosphorylation of STAT3 in eutopic endometrium of infertile women with this disorder leading to o...

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Autores principales: Jung-Yoon Yoo, Tae Hoon Kim, Asgerally T. Fazleabas, Wilder A. Palomino, Soo Hyun Ahn, Chandrakant Tayade, David P. Schammel, Steven L. Young, Jae-Wook Jeong, Bruce A. Lessey
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/8511e65b6d0145d4b9e1880673eb0c3f
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