The predominance of nucleotidyl activation in bacterial phosphonate biosynthesis

Phosphonate modifications can be present on microbial cell surfaces. Here the authors perform bioinformatics analyses and observe a widespread occurrence of nucleotidyltransferase-encoding genes in bacterial phosphonate biosynthesis and functionally characterize two of the identified phosphonate spe...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Kyle Rice, Kissa Batul, Jacqueline Whiteside, Jayne Kelso, Monica Papinski, Edward Schmidt, Alena Pratasouskaya, Dacheng Wang, Rebecca Sullivan, Christopher Bartlett, Joel T. Weadge, Marc W. Van der Kamp, Gabriel Moreno-Hagelsieb, Michael D. Suits, Geoff P. Horsman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/851a3355841b4f708a43a502942c9977
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:851a3355841b4f708a43a502942c9977
record_format	dspace
spelling	oai:doaj.org-article:851a3355841b4f708a43a502942c99772021-12-02T14:39:19ZThe predominance of nucleotidyl activation in bacterial phosphonate biosynthesis10.1038/s41467-019-11627-62041-1723https://doaj.org/article/851a3355841b4f708a43a502942c99772019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11627-6https://doaj.org/toc/2041-1723Phosphonate modifications can be present on microbial cell surfaces. Here the authors perform bioinformatics analyses and observe a widespread occurrence of nucleotidyltransferase-encoding genes in bacterial phosphonate biosynthesis and functionally characterize two of the identified phosphonate specific cytidylyltransferases (PntCs) and determine the crystal structure of T. denticola PntC.Kyle RiceKissa BatulJacqueline WhitesideJayne KelsoMonica PapinskiEdward SchmidtAlena PratasouskayaDacheng WangRebecca SullivanChristopher BartlettJoel T. WeadgeMarc W. Van der KampGabriel Moreno-HagelsiebMichael D. SuitsGeoff P. HorsmanNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kyle Rice Kissa Batul Jacqueline Whiteside Jayne Kelso Monica Papinski Edward Schmidt Alena Pratasouskaya Dacheng Wang Rebecca Sullivan Christopher Bartlett Joel T. Weadge Marc W. Van der Kamp Gabriel Moreno-Hagelsieb Michael D. Suits Geoff P. Horsman The predominance of nucleotidyl activation in bacterial phosphonate biosynthesis
description	Phosphonate modifications can be present on microbial cell surfaces. Here the authors perform bioinformatics analyses and observe a widespread occurrence of nucleotidyltransferase-encoding genes in bacterial phosphonate biosynthesis and functionally characterize two of the identified phosphonate specific cytidylyltransferases (PntCs) and determine the crystal structure of T. denticola PntC.
format	article
author	Kyle Rice Kissa Batul Jacqueline Whiteside Jayne Kelso Monica Papinski Edward Schmidt Alena Pratasouskaya Dacheng Wang Rebecca Sullivan Christopher Bartlett Joel T. Weadge Marc W. Van der Kamp Gabriel Moreno-Hagelsieb Michael D. Suits Geoff P. Horsman
author_facet	Kyle Rice Kissa Batul Jacqueline Whiteside Jayne Kelso Monica Papinski Edward Schmidt Alena Pratasouskaya Dacheng Wang Rebecca Sullivan Christopher Bartlett Joel T. Weadge Marc W. Van der Kamp Gabriel Moreno-Hagelsieb Michael D. Suits Geoff P. Horsman
author_sort	Kyle Rice
title	The predominance of nucleotidyl activation in bacterial phosphonate biosynthesis
title_short	The predominance of nucleotidyl activation in bacterial phosphonate biosynthesis
title_full	The predominance of nucleotidyl activation in bacterial phosphonate biosynthesis
title_fullStr	The predominance of nucleotidyl activation in bacterial phosphonate biosynthesis
title_full_unstemmed	The predominance of nucleotidyl activation in bacterial phosphonate biosynthesis
title_sort	predominance of nucleotidyl activation in bacterial phosphonate biosynthesis
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/851a3355841b4f708a43a502942c9977
work_keys_str_mv	AT kylerice thepredominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT kissabatul thepredominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT jacquelinewhiteside thepredominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT jaynekelso thepredominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT monicapapinski thepredominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT edwardschmidt thepredominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT alenapratasouskaya thepredominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT dachengwang thepredominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT rebeccasullivan thepredominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT christopherbartlett thepredominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT joeltweadge thepredominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT marcwvanderkamp thepredominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT gabrielmorenohagelsieb thepredominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT michaeldsuits thepredominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT geoffphorsman thepredominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT kylerice predominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT kissabatul predominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT jacquelinewhiteside predominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT jaynekelso predominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT monicapapinski predominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT edwardschmidt predominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT alenapratasouskaya predominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT dachengwang predominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT rebeccasullivan predominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT christopherbartlett predominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT joeltweadge predominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT marcwvanderkamp predominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT gabrielmorenohagelsieb predominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT michaeldsuits predominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis AT geoffphorsman predominanceofnucleotidylactivationinbacterialphosphonatebiosynthesis
_version_	1718390666530127872

The predominance of nucleotidyl activation in bacterial phosphonate biosynthesis

Ejemplares similares