The virulent, emerging genotype B of Deformed wing virus is closely linked to overwinter honeybee worker loss

Abstract Bees are considered to be threatened globally, with severe overwinter losses of the most important commercial pollinator, the Western honeybee, a major concern in the Northern Hemisphere. Emerging infectious diseases have risen to prominence due to their temporal correlation with colony los...

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Autores principales:	Myrsini E. Natsopoulou, Dino P. McMahon, Vincent Doublet, Eva Frey, Peter Rosenkranz, Robert J. Paxton
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/8522fe51081b4993a8f52bd2dbca1a2b
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spelling	oai:doaj.org-article:8522fe51081b4993a8f52bd2dbca1a2b2021-12-02T12:30:26ZThe virulent, emerging genotype B of Deformed wing virus is closely linked to overwinter honeybee worker loss10.1038/s41598-017-05596-32045-2322https://doaj.org/article/8522fe51081b4993a8f52bd2dbca1a2b2017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-05596-3https://doaj.org/toc/2045-2322Abstract Bees are considered to be threatened globally, with severe overwinter losses of the most important commercial pollinator, the Western honeybee, a major concern in the Northern Hemisphere. Emerging infectious diseases have risen to prominence due to their temporal correlation with colony losses. Among these is Deformed wing virus (DWV), which has been frequently linked to colony mortality. We now provide evidence of a strong statistical association between overwintering colony decline in the field and the presence of DWV genotype-B (DWV-B), a genetic variant of DWV that has recently been shown to be more virulent than the original DWV genotype-A. We link the prevalence of DWV-B directly to a quantitative measure of overwinter decline (workforce mortality) of honeybee colonies in the field. We demonstrate that increased prevalence of virus infection in individual bees is associated with higher overwinter mortality. We also observed a substantial reduction of infected colonies in the spring, suggesting that virus-infected individuals had died during the winter. Our findings demonstrate that DWV-B, plus possible A/B recombinants exhibiting DWV-B at PCR primer binding sites, may be a major cause of elevated overwinter honeybee loss. Its potential emergence in naïve populations of bees may have far-reaching ecological and economic impacts.Myrsini E. NatsopoulouDino P. McMahonVincent DoubletEva FreyPeter RosenkranzRobert J. PaxtonNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Myrsini E. Natsopoulou Dino P. McMahon Vincent Doublet Eva Frey Peter Rosenkranz Robert J. Paxton The virulent, emerging genotype B of Deformed wing virus is closely linked to overwinter honeybee worker loss
description	Abstract Bees are considered to be threatened globally, with severe overwinter losses of the most important commercial pollinator, the Western honeybee, a major concern in the Northern Hemisphere. Emerging infectious diseases have risen to prominence due to their temporal correlation with colony losses. Among these is Deformed wing virus (DWV), which has been frequently linked to colony mortality. We now provide evidence of a strong statistical association between overwintering colony decline in the field and the presence of DWV genotype-B (DWV-B), a genetic variant of DWV that has recently been shown to be more virulent than the original DWV genotype-A. We link the prevalence of DWV-B directly to a quantitative measure of overwinter decline (workforce mortality) of honeybee colonies in the field. We demonstrate that increased prevalence of virus infection in individual bees is associated with higher overwinter mortality. We also observed a substantial reduction of infected colonies in the spring, suggesting that virus-infected individuals had died during the winter. Our findings demonstrate that DWV-B, plus possible A/B recombinants exhibiting DWV-B at PCR primer binding sites, may be a major cause of elevated overwinter honeybee loss. Its potential emergence in naïve populations of bees may have far-reaching ecological and economic impacts.
format	article
author	Myrsini E. Natsopoulou Dino P. McMahon Vincent Doublet Eva Frey Peter Rosenkranz Robert J. Paxton
author_facet	Myrsini E. Natsopoulou Dino P. McMahon Vincent Doublet Eva Frey Peter Rosenkranz Robert J. Paxton
author_sort	Myrsini E. Natsopoulou
title	The virulent, emerging genotype B of Deformed wing virus is closely linked to overwinter honeybee worker loss
title_short	The virulent, emerging genotype B of Deformed wing virus is closely linked to overwinter honeybee worker loss
title_full	The virulent, emerging genotype B of Deformed wing virus is closely linked to overwinter honeybee worker loss
title_fullStr	The virulent, emerging genotype B of Deformed wing virus is closely linked to overwinter honeybee worker loss
title_full_unstemmed	The virulent, emerging genotype B of Deformed wing virus is closely linked to overwinter honeybee worker loss
title_sort	virulent, emerging genotype b of deformed wing virus is closely linked to overwinter honeybee worker loss
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/8522fe51081b4993a8f52bd2dbca1a2b
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The virulent, emerging genotype B of Deformed wing virus is closely linked to overwinter honeybee worker loss

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