Bayesian modeling of the yeast SH3 domain interactome predicts spatiotemporal dynamics of endocytosis proteins.

SH3 domains are peptide recognition modules that mediate the assembly of diverse biological complexes. We scanned billions of phage-displayed peptides to map the binding specificities of the SH3 domain family in the budding yeast, Saccharomyces cerevisiae. Although most of the SH3 domains fall into...

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Auteurs principaux:	Raffi Tonikian, Xiaofeng Xin, Christopher P Toret, David Gfeller, Christiane Landgraf, Simona Panni, Serena Paoluzi, Luisa Castagnoli, Bridget Currell, Somasekar Seshagiri, Haiyuan Yu, Barbara Winsor, Marc Vidal, Mark B Gerstein, Gary D Bader, Rudolf Volkmer, Gianni Cesareni, David G Drubin, Philip M Kim, Sachdev S Sidhu, Charles Boone
Format:	article
Langue:	EN
Publié:	Public Library of Science (PLoS) 2009
Sujets:	Biology (General) QH301-705.5
Accès en ligne:	https://doaj.org/article/8523eb39b4ed44aa980f11ba6972eb54
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Bayesian modeling of the yeast SH3 domain interactome predicts spatiotemporal dynamics of endocytosis proteins.

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