DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia

Sustained sperm production is dependent on activity of undifferentiated spermatogonia. Here, the authors demonstrate an essential role for RNA helicase DDX5 in maintenance of spermatogonia in adults through control of gene transcription plus RNA processing and export.

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Detalles Bibliográficos
Autores principales:	Julien M. D. Legrand, Ai-Leen Chan, Hue M. La, Fernando J. Rossello, Minna-Liisa Änkö, Frances V. Fuller-Pace, Robin M. Hobbs
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/852498ee4d314917b02f782d466e190b
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spelling	oai:doaj.org-article:852498ee4d314917b02f782d466e190b2021-12-02T16:57:45ZDDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia10.1038/s41467-019-09972-72041-1723https://doaj.org/article/852498ee4d314917b02f782d466e190b2019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09972-7https://doaj.org/toc/2041-1723Sustained sperm production is dependent on activity of undifferentiated spermatogonia. Here, the authors demonstrate an essential role for RNA helicase DDX5 in maintenance of spermatogonia in adults through control of gene transcription plus RNA processing and export.Julien M. D. LegrandAi-Leen ChanHue M. LaFernando J. RosselloMinna-Liisa ÄnköFrances V. Fuller-PaceRobin M. HobbsNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-21 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Julien M. D. Legrand Ai-Leen Chan Hue M. La Fernando J. Rossello Minna-Liisa Änkö Frances V. Fuller-Pace Robin M. Hobbs DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia
description	Sustained sperm production is dependent on activity of undifferentiated spermatogonia. Here, the authors demonstrate an essential role for RNA helicase DDX5 in maintenance of spermatogonia in adults through control of gene transcription plus RNA processing and export.
format	article
author	Julien M. D. Legrand Ai-Leen Chan Hue M. La Fernando J. Rossello Minna-Liisa Änkö Frances V. Fuller-Pace Robin M. Hobbs
author_facet	Julien M. D. Legrand Ai-Leen Chan Hue M. La Fernando J. Rossello Minna-Liisa Änkö Frances V. Fuller-Pace Robin M. Hobbs
author_sort	Julien M. D. Legrand
title	DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia
title_short	DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia
title_full	DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia
title_fullStr	DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia
title_full_unstemmed	DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia
title_sort	ddx5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/852498ee4d314917b02f782d466e190b
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DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia

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