Factor H binding proteins protect division septa on encapsulated Streptococcus pneumoniae against complement C3b deposition and amplification

Streptococcus pneumoniae evades the action of the complement system by expressing an immuno-protective polysaccharide capsule as well as Factor H-binding proteins. Here, Pathak et al. show that these two defence mechanisms are functionally and spatially coordinated on the bacterial cell surface.

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Autores principales:	Anuj Pathak, Jan Bergstrand, Vicky Sender, Laura Spelmink, Marie-Stephanie Aschtgen, Sandra Muschiol, Jerker Widengren, Birgitta Henriques-Normark
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8527c8ca2a884b3ebb6175e9bcdd62be
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spelling	oai:doaj.org-article:8527c8ca2a884b3ebb6175e9bcdd62be2021-12-02T16:50:09ZFactor H binding proteins protect division septa on encapsulated Streptococcus pneumoniae against complement C3b deposition and amplification10.1038/s41467-018-05494-w2041-1723https://doaj.org/article/8527c8ca2a884b3ebb6175e9bcdd62be2018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05494-whttps://doaj.org/toc/2041-1723Streptococcus pneumoniae evades the action of the complement system by expressing an immuno-protective polysaccharide capsule as well as Factor H-binding proteins. Here, Pathak et al. show that these two defence mechanisms are functionally and spatially coordinated on the bacterial cell surface.Anuj PathakJan BergstrandVicky SenderLaura SpelminkMarie-Stephanie AschtgenSandra MuschiolJerker WidengrenBirgitta Henriques-NormarkNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anuj Pathak Jan Bergstrand Vicky Sender Laura Spelmink Marie-Stephanie Aschtgen Sandra Muschiol Jerker Widengren Birgitta Henriques-Normark Factor H binding proteins protect division septa on encapsulated Streptococcus pneumoniae against complement C3b deposition and amplification
description	Streptococcus pneumoniae evades the action of the complement system by expressing an immuno-protective polysaccharide capsule as well as Factor H-binding proteins. Here, Pathak et al. show that these two defence mechanisms are functionally and spatially coordinated on the bacterial cell surface.
format	article
author	Anuj Pathak Jan Bergstrand Vicky Sender Laura Spelmink Marie-Stephanie Aschtgen Sandra Muschiol Jerker Widengren Birgitta Henriques-Normark
author_facet	Anuj Pathak Jan Bergstrand Vicky Sender Laura Spelmink Marie-Stephanie Aschtgen Sandra Muschiol Jerker Widengren Birgitta Henriques-Normark
author_sort	Anuj Pathak
title	Factor H binding proteins protect division septa on encapsulated Streptococcus pneumoniae against complement C3b deposition and amplification
title_short	Factor H binding proteins protect division septa on encapsulated Streptococcus pneumoniae against complement C3b deposition and amplification
title_full	Factor H binding proteins protect division septa on encapsulated Streptococcus pneumoniae against complement C3b deposition and amplification
title_fullStr	Factor H binding proteins protect division septa on encapsulated Streptococcus pneumoniae against complement C3b deposition and amplification
title_full_unstemmed	Factor H binding proteins protect division septa on encapsulated Streptococcus pneumoniae against complement C3b deposition and amplification
title_sort	factor h binding proteins protect division septa on encapsulated streptococcus pneumoniae against complement c3b deposition and amplification
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/8527c8ca2a884b3ebb6175e9bcdd62be
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Factor H binding proteins protect division septa on encapsulated Streptococcus pneumoniae against complement C3b deposition and amplification

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