Factor H binding proteins protect division septa on encapsulated Streptococcus pneumoniae against complement C3b deposition and amplification

Streptococcus pneumoniae evades the action of the complement system by expressing an immuno-protective polysaccharide capsule as well as Factor H-binding proteins. Here, Pathak et al. show that these two defence mechanisms are functionally and spatially coordinated on the bacterial cell surface.

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Bibliographic Details
Main Authors: Anuj Pathak, Jan Bergstrand, Vicky Sender, Laura Spelmink, Marie-Stephanie Aschtgen, Sandra Muschiol, Jerker Widengren, Birgitta Henriques-Normark
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/8527c8ca2a884b3ebb6175e9bcdd62be
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