Monoclonal antibodies block transmission of genetically diverse Plasmodium falciparum strains to mosquitoes

Abstract Malaria parasite transmission to mosquitoes relies on the uptake of sexual stage parasites during a blood meal and subsequent formation of oocysts on the mosquito midgut wall. Transmission-blocking vaccines (TBVs) and monoclonal antibodies (mAbs) target sexual stage antigens to interrupt hu...

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Autores principales: Roos M. de Jong, Lisette Meerstein-Kessel, Dari F. Da, Sandrine Nsango, Joseph D. Challenger, Marga van de Vegte-Bolmer, Geert-Jan van Gemert, Elias Duarte, Noam Teyssier, Robert W. Sauerwein, Thomas S. Churcher, Roch K. Dabire, Isabelle Morlais, Emily Locke, Martijn A. Huynen, Teun Bousema, Matthijs M. Jore
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/852c3163e8664f10865e9f61f43db532
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