HUMORAL IMMUNE RESPONSE TO HIV-1 INFECTION AND ALTERED FUNCTION OF B LYMPHOCYTES

Abstract. Over past years, extensive studies were dedicated to pathogenetic mechanisms of HIV-associated disease. In addition to progressive decrease and dysfunction of CD4+T cells, HIV-1 infection also causes intensive defects of humoral immune links. Absence of antiviral immune control leads to in...

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Autor principal:	S. A. Ketlinsky
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	hiv-1 b cells apoptosis vaccine Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/8545cc2dd7004423abb4da99c3f4ee89
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spelling	oai:doaj.org-article:8545cc2dd7004423abb4da99c3f4ee892021-11-18T08:03:40ZHUMORAL IMMUNE RESPONSE TO HIV-1 INFECTION AND ALTERED FUNCTION OF B LYMPHOCYTES1563-06252313-741X10.15789/1563-0625-2012-3-183-188https://doaj.org/article/8545cc2dd7004423abb4da99c3f4ee892014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/344https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. Over past years, extensive studies were dedicated to pathogenetic mechanisms of HIV-associated disease. In addition to progressive decrease and dysfunction of CD4+T cells, HIV-1 infection also causes intensive defects of humoral immune links. Absence of antiviral immune control leads to infection, and this presents great obstacles when treating the disease and developing an effective vaccine against HIV-1 infection. This review article concerns some features of humoral immunity and disturbed B lymphocyte functions that are studied to lesser degree, with respect to HIV infection pathogenesis.S. A. KetlinskySPb RAACIarticlehiv-1b cellsapoptosisvaccineImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 14, Iss 3, Pp 183-188 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	hiv-1 b cells apoptosis vaccine Immunologic diseases. Allergy RC581-607
spellingShingle	hiv-1 b cells apoptosis vaccine Immunologic diseases. Allergy RC581-607 S. A. Ketlinsky HUMORAL IMMUNE RESPONSE TO HIV-1 INFECTION AND ALTERED FUNCTION OF B LYMPHOCYTES
description	Abstract. Over past years, extensive studies were dedicated to pathogenetic mechanisms of HIV-associated disease. In addition to progressive decrease and dysfunction of CD4+T cells, HIV-1 infection also causes intensive defects of humoral immune links. Absence of antiviral immune control leads to infection, and this presents great obstacles when treating the disease and developing an effective vaccine against HIV-1 infection. This review article concerns some features of humoral immunity and disturbed B lymphocyte functions that are studied to lesser degree, with respect to HIV infection pathogenesis.
format	article
author	S. A. Ketlinsky
author_facet	S. A. Ketlinsky
author_sort	S. A. Ketlinsky
title	HUMORAL IMMUNE RESPONSE TO HIV-1 INFECTION AND ALTERED FUNCTION OF B LYMPHOCYTES
title_short	HUMORAL IMMUNE RESPONSE TO HIV-1 INFECTION AND ALTERED FUNCTION OF B LYMPHOCYTES
title_full	HUMORAL IMMUNE RESPONSE TO HIV-1 INFECTION AND ALTERED FUNCTION OF B LYMPHOCYTES
title_fullStr	HUMORAL IMMUNE RESPONSE TO HIV-1 INFECTION AND ALTERED FUNCTION OF B LYMPHOCYTES
title_full_unstemmed	HUMORAL IMMUNE RESPONSE TO HIV-1 INFECTION AND ALTERED FUNCTION OF B LYMPHOCYTES
title_sort	humoral immune response to hiv-1 infection and altered function of b lymphocytes
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/8545cc2dd7004423abb4da99c3f4ee89
work_keys_str_mv	AT saketlinsky humoralimmuneresponsetohiv1infectionandalteredfunctionofblymphocytes
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HUMORAL IMMUNE RESPONSE TO HIV-1 INFECTION AND ALTERED FUNCTION OF B LYMPHOCYTES

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