The increasing burden of depression

Jean-Pierre L&eacute;pine1, Mike Briley21H&ocirc;pital Lariboisi&egrave;re Fernand Widal, Assistance Publique H&ocirc;pitaux de Paris Unit&eacute; INSERM 705 CNRS UMR 8206, Universit&eacute; Paris Diderot, Paris, France; 2NeuroBiz Consulting and Commun...

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Autores principales:	L&eacute;pine J-P, Briley M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2011
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/854a952c794949cb8b4c152b477c006f
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spelling	oai:doaj.org-article:854a952c794949cb8b4c152b477c006f2021-12-02T08:30:27ZThe increasing burden of depression1176-63281178-2021https://doaj.org/article/854a952c794949cb8b4c152b477c006f2011-05-01T00:00:00Zhttp://www.dovepress.com/the-increasing-burden-of-depression-a7566https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Jean-Pierre L&eacute;pine1, Mike Briley21H&ocirc;pital Lariboisi&egrave;re Fernand Widal, Assistance Publique H&ocirc;pitaux de Paris Unit&eacute; INSERM 705 CNRS UMR 8206, Universit&eacute; Paris Diderot, Paris, France; 2NeuroBiz Consulting and Communication, Castres, FranceAbstract: Recent epidemiological surveys conducted in general populations have found that the lifetime prevalence of depression is in the range of 10% to 15%. Mood disorders, as defined by the World Mental Health and the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, have a 12-month prevalence which varies from 3% in Japan to over 9% in the US. A recent American survey found the prevalence of current depression to be 9% and the rate of current major depression to be 3.4%. All studies of depressive disorders have stressed the importance of the mortality and morbidity associated with depression. The mortality risk for suicide in depressed patients is more than 20-fold greater than in the general population. Recent studies have also shown the importance of depression as a risk factor for cardiovascular death. The risk of cardiac mortality after an initial myocardial infarction is greater in patients with depression and related to the severity of the depressive episode. Greater severity of depressive symptoms has been found to be associated with significantly higher risk of all-cause mortality including cardiovascular death and stroke. In addition to mortality, functional impairment and disability associated with depression have been consistently reported. Depression increases the risk of decreased workplace productivity and absenteeism resulting in lowered income or unemployment. Absenteeism and presenteeism (being physically present at work but functioning suboptimally) have been estimated to result in a loss of $36.6 billion per year in the US. Worldwide projections by the World Health Organization for the year 2030 identify unipolar major depression as the leading cause of disease burden. This article is a brief overview of how depression affects the quality of life of the subject and is also a huge burden for both the family of the depressed patient and for society at large.Keywords: epidemiology, DALY, mortality risk, economic burden, family burden, depressionL&eacute;pine J-PBriley MDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2011, Iss Supplement 1, Pp 3-7 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 L&eacute;pine J-P Briley M The increasing burden of depression
description	Jean-Pierre L&eacute;pine1, Mike Briley21H&ocirc;pital Lariboisi&egrave;re Fernand Widal, Assistance Publique H&ocirc;pitaux de Paris Unit&eacute; INSERM 705 CNRS UMR 8206, Universit&eacute; Paris Diderot, Paris, France; 2NeuroBiz Consulting and Communication, Castres, FranceAbstract: Recent epidemiological surveys conducted in general populations have found that the lifetime prevalence of depression is in the range of 10% to 15%. Mood disorders, as defined by the World Mental Health and the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, have a 12-month prevalence which varies from 3% in Japan to over 9% in the US. A recent American survey found the prevalence of current depression to be 9% and the rate of current major depression to be 3.4%. All studies of depressive disorders have stressed the importance of the mortality and morbidity associated with depression. The mortality risk for suicide in depressed patients is more than 20-fold greater than in the general population. Recent studies have also shown the importance of depression as a risk factor for cardiovascular death. The risk of cardiac mortality after an initial myocardial infarction is greater in patients with depression and related to the severity of the depressive episode. Greater severity of depressive symptoms has been found to be associated with significantly higher risk of all-cause mortality including cardiovascular death and stroke. In addition to mortality, functional impairment and disability associated with depression have been consistently reported. Depression increases the risk of decreased workplace productivity and absenteeism resulting in lowered income or unemployment. Absenteeism and presenteeism (being physically present at work but functioning suboptimally) have been estimated to result in a loss of $36.6 billion per year in the US. Worldwide projections by the World Health Organization for the year 2030 identify unipolar major depression as the leading cause of disease burden. This article is a brief overview of how depression affects the quality of life of the subject and is also a huge burden for both the family of the depressed patient and for society at large.Keywords: epidemiology, DALY, mortality risk, economic burden, family burden, depression
format	article
author	L&eacute;pine J-P Briley M
author_facet	L&eacute;pine J-P Briley M
author_sort	L&eacute;pine J-P
title	The increasing burden of depression
title_short	The increasing burden of depression
title_full	The increasing burden of depression
title_fullStr	The increasing burden of depression
title_full_unstemmed	The increasing burden of depression
title_sort	increasing burden of depression
publisher	Dove Medical Press
publishDate	2011
url	https://doaj.org/article/854a952c794949cb8b4c152b477c006f
work_keys_str_mv	AT lampeacutepinejp theincreasingburdenofdepression AT brileym theincreasingburdenofdepression AT lampeacutepinejp increasingburdenofdepression AT brileym increasingburdenofdepression
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The increasing burden of depression

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